Tuesday, March 08, 2011

ABSTRACT: Language skills of school-aged children prenatally exposed to antiepileptic drugs.
Nadebaum C, Anderson VA, Vajda F, Reutens DC, Barton S, Wood AG.
School of Psychology, University of Birmingham, Edgbaston, B15 2TT, UK a.g.wood@bham.ac.uk.
Neurology. 2011 Feb 22;76(8):719-26.

Abstract
OBJECTIVES: Fetal exposure to some antiepileptic drugs (AEDs) carries increased risk of major birth defects, and may be associated with reduced intellectual abilities. The impact on language remains unclear. This study aimed to investigate the impact of fetal AED exposure on language skills.

CONCLUSIONS: Fetal exposure to sodium valproate increases the risk of language impairment. This should be taken into account when making treatment decisions for women with epilepsy of childbearing age.

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