tag:blogger.com,1999:blog-288980422024-03-06T01:05:11.611-06:00News: Pediatric Neurology Epilepsy Sleep Medicine Brain Injury - Houston Children & FamiliesInformation, News & Discussion about Infant Pediatric & Adolescent Neurology & Sleep Disorders. Science Diagnostics Symptoms Treatment. Topics include: Seizures Epilepsy Spasticity Developmental Disorders Cerebral Palsy Headaches Tics Concussion Brain Injury Neurobehavioral Disorders ADHD Autism
Serving Texas Children's Neurology, Epilepsy, Developmental & Sleep Problems in The Houston Area and The San Antonio / Central & South Texas Areas
Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.comBlogger2772125tag:blogger.com,1999:blog-28898042.post-20979654196695186422022-08-06T17:17:00.005-05:002022-08-06T17:17:42.240-05:00<h3 class="post-title entry-title" itemprop="name" style="background-color: white; color: #1a2a2a; font-family: "Josefin Sans"; font-size: 36px; font-stretch: normal; font-variant-east-asian: normal; font-variant-numeric: normal; line-height: normal; margin: 0px; position: relative;">Houston Practice Seeks Outpatient Only</h3><h3 class="post-title entry-title" itemprop="name" style="background-color: white; color: #1a2a2a; font-family: "Josefin Sans"; font-size: 36px; font-stretch: normal; font-variant-east-asian: normal; font-variant-numeric: normal; line-height: normal; margin: 0px; position: relative;">Sleep / Pediatric Neurology NP or PA </h3><h3 class="post-title entry-title" itemprop="name" style="background-color: white; color: #1a2a2a; font-family: "Josefin Sans"; font-size: 36px; font-stretch: normal; font-variant-east-asian: normal; font-variant-numeric: normal; line-height: normal; margin: 0px; position: relative;"><br /></h3><h3 class="post-title entry-title" itemprop="name" style="background-color: white; color: #1a2a2a; font-family: "Josefin Sans"; font-size: 36px; font-stretch: normal; font-variant-east-asian: normal; font-variant-numeric: normal; line-height: normal; margin: 0px; position: relative;">- Make a Difference Every Day!-</h3><div class="post-body entry-content" id="post-body-2547505205469051607" itemprop="description articleBody" style="background-color: white; color: #1a2a2a; line-height: 1.4; position: relative; width: 898px;"><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">JOB DESCRIPTION</span></b><span style="font-family: cambria, serif; font-size: 12pt;"><o:p></o:p></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">Houston Specialty Clinic - Neurology & Sleep Specialists, a regional leader in specialty care has experienced great demand. We offer academic quality care and personal attention. We take care of people experiencing illness or seeking answers to specialty-level concerns.<o:p></o:p></span></b></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">Our practice seeks a PT or FT extender to offer enhanced access to advanced specialty care in sleep disorders and neurologic illness in children. </span></b><span style="font-family: cambria, serif; font-size: 12pt;"><o:p></o:p></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><u><span style="font-family: cambria, serif; font-size: 12pt;">Job Summary</span></u></b><span style="font-family: cambria, serif; font-size: 12pt;">: Under general direction, provides care in collaboration with the neurologist in the evaluation and treatment of pediatric neurologic illness and sleep disorders; serves as a resource person for staff; provides direct clinical service to patients and families including psychosocial assessment, crisis intervention, counseling, complex care management, and patient education.</span><span style="font-family: cambria, serif; font-size: 12pt;"><o:p></o:p></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">CHARACTERISTIC JOB TASKS AND RESPONSIBILITIES</span></b><span style="font-family: cambria, serif; font-size: 12pt;"><o:p></o:p></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">While focusing on outpatient care, duties may include any and/or all of the following:</span></b><span style="font-family: cambria, serif; font-size: 12pt;"><o:p></o:p></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><ol start="1" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-top: 0in;" type="1"><li class="MsoNormal" style="margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Participates in delivering direct patient care; provides instructions and teaching to patients and families; assists in outpatient clinics with examinations and assessments; follows up on lab, test, and procedure results and prescriptions; informs patients of medication changes; informs physicians of patients' questions; evaluates patients' qualifications for clinical research studies; provides initial contact with patient's primary physician; establishes referral database; communicates with referring physicians for follow-up care and referrals.<o:p></o:p></span></li><li class="MsoNormal" style="margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Collaborates with health care team members in planning, implementing, and evaluating comprehensive patient care; provides direct clinical service to patients and families inclduing biopsychosocial assessment, behavior modification, care management, and patient education; researches improvements in patient management, including coordination between services and conservation of resources; facilitates and participates in meetings and projects.<o:p></o:p></span></li><li class="MsoNormal" style="margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Collaborates with established primary care providers as a specialty consulting service</span></li><li class="MsoNormal" style="margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Serves as a resource person and a nurse consultant for staff; develops an annual plan for professional development; attends conferences; maintains and improves current knowledge and competency as a PA or N.P.<o:p></o:p></span></li><li class="MsoNormal" style="margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Perform other duties as assigned.<o:p></o:p></span></li></ol><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">KNOWLEDGE, SKILLS, ABILITIES, AND PERSONAL CHARACTERISTICS</span></b><span style="font-family: cambria, serif; font-size: 12pt;"><o:p></o:p></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><ul style="font-family: "Josefin Sans"; font-size: 15.84px; line-height: 1.4; list-style-image: initial; list-style-position: initial; margin: 0in 0px 0.5em; padding: 0px 2.5em;" type="disc"><li class="MsoNormal" style="border: none; margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Knowledge and experience in Clinical Practice Nursing or as a Physician Assistant<o:p></o:p></span></li><li class="MsoNormal" style="border: none; margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Verbal/written communication skills<o:p></o:p></span></li><li class="MsoNormal" style="border: none; margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Interpersonal/human relations skills<o:p></o:p></span></li><li class="MsoNormal" style="border: none; margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Patient assessment skills<o:p></o:p></span></li><li class="MsoNormal" style="border: none; margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Public speaking skills<o:p></o:p></span></li><li class="MsoNormal" style="border: none; margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Research skills<o:p></o:p></span></li><li class="MsoNormal" style="border: none; margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Ability to respond to questions in a tactful and professional manner<o:p></o:p></span></li><li class="MsoNormal" style="border: none; margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Ability to instruct/teach/tutor<o:p></o:p></span></li><li class="MsoNormal" style="border: none; margin: 0px 0px 0.0001pt; padding: 0px; vertical-align: baseline;"><span style="font-family: cambria, serif; font-size: 12pt;">Ability to maintain confidentiality</span><span style="font-family: cambria, serif; font-size: 12pt;"><br /><br /></span><span style="font-family: cambria, serif; font-size: 12pt;"><o:p></o:p></span></li></ul><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">MINIMUM QUALIFICATIONS:<o:p></o:p></span></b></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">Education and experience equivalent to:</span></b><span style="font-family: cambria, serif; font-size: 12pt;"><o:p></o:p></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif; font-size: 12pt;">Master's degree in nursing and certification in a specialty area of a Clinical Nurse Specialist or Nurse Practitioner; supplemented with two (2) years of related experience. Texas RN License and certification as an Advanced Practice Nurse required.<o:p></o:p></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><div style="text-align: center;">OR </div></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif; font-size: 12pt;">TX PA licensure </span><span style="font-family: cambria, serif; font-size: 12pt;">supplemented with two (2) years of related experience</span><span style="font-family: cambria, serif; font-size: 12pt;"><o:p></o:p></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">Physical Requirements</span></b><span style="font-family: cambria, serif; font-size: 12pt;"> – Typical for an outpatient clinic. </span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif; font-size: 12pt;">May require some driving to satellite clinics. </span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif; font-size: 12pt;">Duties include telemedicine visits.<br /><o:p></o:p></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif; font-size: 12pt;"><br /></span></div><div class="MsoNormal" style="margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif;">Must be comfortable with children and adults with neurologic and developmental disorders</span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif; font-size: 12pt;"><br /></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif; font-size: 12pt;">Competitive Salary & Productivity Bonus Commensurate with Experience</span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif; font-size: 12pt;"><br /></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif; font-size: 12pt;">We welcome applicants for Part-Time and Full Time Work</span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif; font-size: 12pt;"><br /></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><span style="font-family: cambria, serif; font-size: 12pt;">HSC offers eligible employees a broad package of benefits such as health care, dental plan, vision plan, 401K.<o:p></o:p></span></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><br /></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">Contact Dr. Joshua Rotenberg<o:p></o:p></span></b><br /><b><span style="font-family: cambria, serif; font-size: 12pt;">clinicrotenberg@houstonspecialtyclinic.com</span></b></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">713-464-4107<o:p></o:p></span></b></div><div class="MsoNormal" style="font-family: "Josefin Sans"; font-size: 15.84px; margin-bottom: 0.0001pt;"><b><span style="font-family: cambria, serif; font-size: 12pt;">Fax 713-465-4522</span></b><b><span style="font-family: cambria, serif; font-size: 12pt;"><o:p></o:p></span></b></div><div style="font-family: "Josefin Sans"; font-size: 15.84px;"><b><span style="font-family: cambria, serif; font-size: 12pt;"><br /></span></b></div></div>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-11945410657388086612021-04-18T19:10:00.002-05:002021-04-19T11:05:30.102-05:00Neuromodulation for appetite control in Prader Willi <p><br /></p><p>More literature how TDCS can modify food craving in Prader Willi. </p><p>Call our office for an appointment to see if your child is a candidate. </p><div class="html-abstract-title" style="-webkit-text-size-adjust: 100%; box-sizing: border-box; caret-color: rgb(34, 34, 34); color: #222222; font-family: Arial, Arial, Helvetica, sans-serif; font-size: 13.199999809265137px; margin: 0px; max-height: 1000000px; padding: 0px;"><h2 style="box-sizing: border-box; color: black; font-size: 13.199999809265137px; line-height: 1.5; margin: 30px 0px 10px; max-height: 1000000px; padding: 0.5em 0px; text-rendering: optimizeLegibility;">Abstract</h2></div><div class="art-abstract in-tab hypothesis_container" style="-webkit-text-size-adjust: 100%; box-sizing: border-box; caret-color: rgb(34, 34, 34); color: #222222; display: inline-block; font-family: Arial, Arial, Helvetica, sans-serif; font-size: 13.199999809265137px; margin: 0px; max-height: 1000000px; padding: 0px;">Prader–Willi syndrome (PWS) is a neurodevelopmental genetic disorder characterized by multiple system involvement with hypotonia, poor suck with feeding difficulties, growth and other hormone deficiencies, intellectual disability, and behavioral problems with childhood onset of hyperphagia resulting in obesity, if not externally controlled. Transcranial direct current stimulation (tDCS) has been increasingly shown to modulate cognitive and behavioral processes in children and adults, including food-intake behaviors in patients with PWS. This study further reports the positive effects of brief tDCS sessions on Go/NoGo task performance involving food and non-food stimuli images, alterations in N2 brain amplitude, and genetic subgroup differences (maternal disomy 15, UPD; 15q11-q13 deletion, DEL) before and after tDCS as assessed by event-related potentials (ERPs) in 10 adults with PWS. The results indicate a group effect on baseline NoGo N2 amplitude in PWS patients with DEL vs UPD (<span class="html-italic" style="box-sizing: border-box; display: inline; font-style: italic; max-height: 1000000px;">p</span> =0.046) and a decrease in NoGo N2 amplitude following tDCS (<span class="html-italic" style="box-sizing: border-box; display: inline; font-style: italic; max-height: 1000000px;">p</span> = 0.031). Our tDCS approach also demonstrated a trend towards decreased response time. Collectively, these results replicate and expand prior work highlighting neurophysiological differences in patients with PWS according to genetic subtype and demonstrate the feasibility in examining neuromodulatory effects of tDCS on information processing in this patient population to stimulate additional research and treatment.</div><p><br /></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhKIb9oHznKksFV1EUYPVqm2gAWoFRcA6GGZFyJ8ETVGO8UK4rphgV0E522MxcIMarSeeTcEMDctwjQBna7_F0OPdFUXrN3St7BdmCHVSGLWp3ptWyJoIOSQfLXzgSoqALARR0q/s1542/0CD3BD8F-120C-4935-B1AC-FBA13AE3C51A.jpeg" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img alt="Transcranial stimulation may reduce appetite in Prader Willi" border="0" data-original-height="1542" data-original-width="1078" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhKIb9oHznKksFV1EUYPVqm2gAWoFRcA6GGZFyJ8ETVGO8UK4rphgV0E522MxcIMarSeeTcEMDctwjQBna7_F0OPdFUXrN3St7BdmCHVSGLWp3ptWyJoIOSQfLXzgSoqALARR0q/w224-h320/0CD3BD8F-120C-4935-B1AC-FBA13AE3C51A.jpeg" title="Call For treatment info" width="224" /></a></div><br /><p><br /></p><p><a href="https://praderwillinews.com/2021/04/15/noninvasive-brain-stimulation-suggests-better-appetite-pilot-study/">https://praderwillinews.com/2021/04/15/noninvasive-brain-stimulation-suggests-better-appetite-pilot-study/</a></p><p><br /></p><p><br /></p><p><br /></p><p><br /></p><p><br /></p><p><br /></p>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-85825248151008651572021-02-12T16:03:00.000-06:002021-02-12T16:03:02.348-06:00Covid Vaccine Availability Teens and Adults in Texas <p>Looking for a covid vaccine?</p><p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjk7NwEUxnUjSttOTGYj1YW9vY4t-Hnrg8HSEb8pmkeoyHVT1GmUja0QzSxlyX3pYH-NHQmKRHq281K71Mr038ro8NvQ498GvKcPbptKz63x6Jf00TM0J7pYIIXGgBkubI4NVCB/" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"><img alt="" data-original-height="197" data-original-width="378" height="167" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjk7NwEUxnUjSttOTGYj1YW9vY4t-Hnrg8HSEb8pmkeoyHVT1GmUja0QzSxlyX3pYH-NHQmKRHq281K71Mr038ro8NvQ498GvKcPbptKz63x6Jf00TM0J7pYIIXGgBkubI4NVCB/" width="320" /></a></div><p></p><p>Here is a link </p><p><a href="https://tdem.maps.arcgis.com/apps/webappviewer/index.html?id=3700a84845c5470cb0dc3ddace5c376b"><b>Covid Vaccine Sites Houston Dallas Austin San Antonio</b></a></p>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-30097454162701495362021-02-07T19:28:00.004-06:002021-02-07T19:28:35.006-06:00Concussion Mild Brain Injury in Children Lasts Longer than a Few Weeks<p> </p><p>Hate to spoil the Super Bowl ...</p><p>But, so many kids suffer from brain injury that is unrecognized. It’s true in Houston Texas and elsewhere. </p><p>JR </p><p><br /></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiZjT9A3KFH_gXVFq_w_Qg4RSPIRuniG1aD9iqG0OaZZxBSQtW22innNNRjSkXs754fmY_15BF1ZosdSCJ5_ZvzKeYv83MyHnVvYr_Ntujz0Eda9aWmVZbKIm7yzX5JbXi3M_gM/s1359/9869FF4D-1306-4E7E-A9D0-A64548C5C42C.jpeg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="927" data-original-width="1359" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiZjT9A3KFH_gXVFq_w_Qg4RSPIRuniG1aD9iqG0OaZZxBSQtW22innNNRjSkXs754fmY_15BF1ZosdSCJ5_ZvzKeYv83MyHnVvYr_Ntujz0Eda9aWmVZbKIm7yzX5JbXi3M_gM/s320/9869FF4D-1306-4E7E-A9D0-A64548C5C42C.jpeg" width="320" /></a></div><br /><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhe1I4Ru1bAGyXu22tuVGNtIqEYtoDOPucpe9MMcSlbD2JEcU7EGzg7jyj_yLnMRbZtGV_xKVNhjduw4HFjDD6T37d4Uz6VVemLQwI6pZ-u1fV1cLaersv5sh8fn7vgaQQFoHZB/s1353/D5F856FC-D9D2-4A11-9CB3-16B6D88A0583.jpeg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="825" data-original-width="1353" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhe1I4Ru1bAGyXu22tuVGNtIqEYtoDOPucpe9MMcSlbD2JEcU7EGzg7jyj_yLnMRbZtGV_xKVNhjduw4HFjDD6T37d4Uz6VVemLQwI6pZ-u1fV1cLaersv5sh8fn7vgaQQFoHZB/s320/D5F856FC-D9D2-4A11-9CB3-16B6D88A0583.jpeg" width="320" /></a></div><br /><p><br /></p><p><a href="https://www.houstonspecialtyclinic.com/blog/concussion-mild-brain-injury-in-children-lasts-longer-than-a-few-weeks" target="_blank">Post Here</a></p>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-72092966796819555452021-02-05T11:53:00.005-06:002021-02-05T11:53:43.329-06:00Autism and Maternal Antibodies <p> This is an interesting article about association without a clinical application at this time. </p><p>JR</p><div class="c-article-header" style="background-color: white; box-sizing: inherit; color: #222222; font-family: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, Oxygen-Sans, Ubuntu, Cantarell, "Helvetica Neue", sans-serif; font-size: 18px; margin: 0px 0px 40px; padding: 0px;"><header style="box-sizing: inherit;"><h1 class="c-article-title" data-article-title="" data-test="article-title" itemprop="name headline" style="box-sizing: inherit; font-size: 3rem; line-height: 1.2; margin: 0px 0px 16px; padding: 0px;">Risk assessment analysis for maternal autoantibody-related autism (MAR-ASD): a subtype of autism</h1><ul class="c-author-list js-etal-collapsed js-no-scroll" data-component-authors-activator="authors-list" data-etal-small="3" data-etal="25" data-test="authors-list" style="box-sizing: inherit; font-size: 1.6rem; list-style: none; margin-bottom: 0px; margin-top: 0px; padding: 0px; width: 751.281px;"><li class="c-author-list__item" itemprop="author" itemscope="itemscope" itemtype="http://schema.org/Person" style="box-sizing: inherit; display: inline; margin-left: 0px; padding-right: 0px;"><span itemprop="name" style="box-sizing: inherit;"><a aria-expanded="false" aria-pressed="false" data-author-popup="auth-Alexandra-Ramirez_Celis" data-test="author-name" data-track-action="open author" data-track-label="link" data-track="click" style="background-color: transparent; box-sizing: inherit; color: #006699; vertical-align: baseline;">Alexandra Ramirez-Celis</a></span>, </li><li class="c-author-list__item" itemprop="author" itemscope="itemscope" itemtype="http://schema.org/Person" style="box-sizing: inherit; display: inline; margin-left: 0px; padding-right: 0px;"><span itemprop="name" style="box-sizing: inherit;"><a aria-expanded="false" aria-pressed="false" data-author-popup="auth-Martin-Becker" data-test="author-name" data-track-action="open author" data-track-label="link" data-track="click" style="background-color: transparent; box-sizing: inherit; color: #006699; vertical-align: baseline;">Martin Becker</a></span>, </li><li class="c-author-list__item js-smaller-author-etal" itemprop="author" itemscope="itemscope" itemtype="http://schema.org/Person" style="box-sizing: inherit; display: inline; margin-left: 0px; padding-right: 0px;"><span itemprop="name" style="box-sizing: inherit;"><a aria-expanded="false" aria-pressed="false" data-author-popup="auth-Miriam-Nu_o" data-test="author-name" data-track-action="open author" data-track-label="link" data-track="click" style="background-color: transparent; box-sizing: inherit; color: #006699; vertical-align: baseline;">Miriam Nuño</a></span>, </li><li class="c-author-list__item js-smaller-author-etal" itemprop="author" itemscope="itemscope" itemtype="http://schema.org/Person" style="box-sizing: inherit; display: inline; margin-left: 0px; padding-right: 0px;"><span itemprop="name" style="box-sizing: inherit;"><a aria-expanded="false" aria-pressed="false" data-author-popup="auth-Joseph-Schauer" data-test="author-name" data-track-action="open author" data-track-label="link" data-track="click" style="background-color: transparent; box-sizing: inherit; color: #006699; vertical-align: baseline;">Joseph Schauer</a></span>, </li><li class="c-author-list__item js-smaller-author-etal" itemprop="author" itemscope="itemscope" itemtype="http://schema.org/Person" style="box-sizing: inherit; display: inline; margin-left: 0px; padding-right: 0px;"><span itemprop="name" style="box-sizing: inherit;"><a aria-expanded="false" aria-pressed="false" data-author-popup="auth-Nima-Aghaeepour" data-test="author-name" data-track-action="open author" data-track-label="link" data-track="click" style="background-color: transparent; box-sizing: inherit; color: #006699; vertical-align: baseline;">Nima Aghaeepour</a></span> & </li><li class="c-author-list__item" itemprop="author" itemscope="itemscope" itemtype="http://schema.org/Person" style="box-sizing: inherit; display: inline; margin-left: 0px; padding-right: 0px;"><span itemprop="name" style="box-sizing: inherit;"><a aria-expanded="false" aria-pressed="false" data-author-popup="auth-Judy-Van_de_Water" data-corresp-id="c1" data-test="author-name" data-track-action="open author" data-track-label="link" data-track="click" style="background-color: transparent; box-sizing: inherit; color: #006699; vertical-align: baseline;">Judy Van de Water<svg class="u-icon" height="16" width="16"><use xlink:href="#global-icon-email" xmlns:xlink="http://www.w3.org/1999/xlink"></use></svg></a></span> </li></ul><p class="c-article-info-details" data-container-section="info" style="box-sizing: inherit; font-size: 1.6rem; margin: 16px 0px 8px; padding: 0px;"><a data-test="journal-link" href="https://www.nature.com/mp" style="background-color: transparent; box-sizing: inherit; color: #006699; text-decoration-line: none; vertical-align: baseline;"><i data-test="journal-title" style="box-sizing: inherit;">Molecular Psychiatry</i></a> (<span data-test="article-publication-year" style="box-sizing: inherit;">2021</span>)<a class="c-article-info-details__cite-as u-hide-print" data-track-action="cite this article" data-track-label="link" data-track="click" href="https://www.nature.com/articles/s41380-020-00998-8#citeas" style="background-color: transparent; border-left: 1px solid rgb(111, 111, 111); box-sizing: inherit; color: #006699; margin-left: 8px; padding-left: 8px; text-decoration-line: none; vertical-align: baseline;">Cite this article</a></p><div class="c-article-metrics-bar__wrapper u-clear-both" style="box-sizing: inherit; margin: 0px 0px 16px; padding: 0px;"><ul class="c-article-metrics-bar u-list-reset" style="box-sizing: inherit; display: flex; flex-wrap: wrap; font-size: 1.6rem; line-height: 1.3; list-style: none; margin: 0px; padding: 0px;"><li class=" c-article-metrics-bar__item" style="-webkit-box-align: baseline; align-items: baseline; border-right: 1px solid rgb(111, 111, 111); box-sizing: inherit; margin-right: 8px;"><p class="c-article-metrics-bar__count" style="box-sizing: inherit; font-weight: 700; margin: 0px; padding: 0px;">10k <span class="c-article-metrics-bar__label" style="box-sizing: inherit; color: #626262; font-weight: 400; margin: 0px 10px 0px 5px;">Accesses</span></p></li><li class="c-article-metrics-bar__item" style="-webkit-box-align: baseline; align-items: baseline; border-right: 1px solid rgb(111, 111, 111); box-sizing: inherit; margin-right: 8px;"><p class="c-article-metrics-bar__count" style="box-sizing: inherit; font-weight: 700; margin: 0px; padding: 0px;">177 <span class="c-article-metrics-bar__label" style="box-sizing: inherit; color: #626262; font-weight: 400; margin: 0px 10px 0px 5px;">Altmetric</span></p></li><li class="c-article-metrics-bar__item" style="-webkit-box-align: baseline; align-items: baseline; border-right: 0px; box-sizing: inherit; margin-right: 8px;"><p class="c-article-metrics-bar__details" style="box-sizing: inherit; margin: 0px; padding: 0px;"><a data-track-action="view metrics" data-track-label="link" data-track="click" href="https://www.nature.com/articles/s41380-020-00998-8/metrics" rel="nofollow" style="background-color: transparent; box-sizing: inherit; color: #006699; text-decoration-line: none; vertical-align: baseline;">Metrics<span class="u-visually-hidden" style="border: 0px; box-sizing: inherit; clip: rect(0px, 0px, 0px, 0px); height: 1px; margin: -1672px; overflow: hidden; padding: 0px; position: absolute !important; width: 1px;">details</span></a></p></li></ul></div></header></div><div class="c-article-body" style="background-color: white; box-sizing: inherit; clear: both; color: #222222; font-family: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, Oxygen-Sans, Ubuntu, Cantarell, "Helvetica Neue", sans-serif; font-size: 18px; margin: 0px; padding: 0px;"><section aria-labelledby="Abs1" data-gtm-vis-first-on-screen-10482319_393="363" data-gtm-vis-first-on-screen-10482319_401="363" data-gtm-vis-has-fired-10482319_393="1" data-gtm-vis-has-fired-10482319_401="1" data-gtm-vis-recent-on-screen-10482319_393="363" data-gtm-vis-recent-on-screen-10482319_401="363" data-gtm-vis-total-visible-time-10482319_393="10000" data-gtm-vis-total-visible-time-10482319_401="10000" data-title="Abstract" lang="en" style="box-sizing: inherit;"><div class="c-article-section" id="Abs1-section" style="box-sizing: inherit; clear: both; margin: 0px; padding: 0px;"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Abs1" style="border-bottom: 2px solid rgb(213, 213, 213); box-sizing: inherit; font-size: 2.4rem; line-height: 1.24; margin: 0px 0px 8px; padding: 0px 0px 8px;">Abstract</h2><div class="c-article-section__content" id="Abs1-content" style="box-sizing: inherit; margin: 0px 0px 40px; padding: 0px;"><p style="box-sizing: inherit; margin: 0px 0px 28px; overflow-wrap: break-word; padding: 0px;">The incidence of autism spectrum disorder (ASD) has been rising, however ASD-risk biomarkers remain lacking. We previously identified the presence of maternal autoantibodies to fetal brain proteins specific to ASD, now termed maternal autoantibody-related (MAR) ASD. </p><p style="box-sizing: inherit; margin: 0px 0px 28px; overflow-wrap: break-word; padding: 0px;">The current study aimed to create and validate a serological assay to identify ASD-specific maternal autoantibody patterns of reactivity against eight previously identified proteins (CRMP1, CRMP2, GDA, NSE, LDHA, LDHB, STIP1, and YBOX) that are highly expressed in developing brain, and determine the relationship of these reactivity patterns with ASD outcome severity. We used plasma from mothers of children diagnosed with ASD (<i style="box-sizing: inherit;">n</i> = 450) and from typically developing children (TD, <i style="box-sizing: inherit;">n</i> = 342) to develop an ELISA test for each of the protein antigens. </p><p style="box-sizing: inherit; margin: 0px 0px 28px; overflow-wrap: break-word; padding: 0px;">We then determined patterns of reactivity a highly significant association with ASD, and discovered several patterns that were ASD-specific (18% in the training set and 10% in the validation set vs. 0% TD). </p><p style="box-sizing: inherit; margin: 0px 0px 28px; overflow-wrap: break-word; padding: 0px;">The three main patterns associated with MAR ASD are</p><p style="box-sizing: inherit; margin: 0px 0px 28px; overflow-wrap: break-word; padding: 0px;"></p><ul style="text-align: left;"><li>CRMP1 + GDA (ASD% = 4.2 vs. TD% = 0, OR 31.04, <i style="box-sizing: inherit;">p</i> = <0.0001), </li><li>CRMP1 + CRMP2 (ASD% = 3.6 vs. TD% = 0, OR 26.08, <i style="box-sizing: inherit;">p</i> = 0.0005) </li><li>NSE + STIP1 (ASD% = 3.1 vs. TD% = 0, OR 22.82, <i style="box-sizing: inherit;">p</i> = 0.0001). </li></ul><p></p><p style="box-sizing: inherit; margin: 0px 0px 28px; overflow-wrap: break-word; padding: 0px;">Additionally, we found that maternal autoantibody reactivity to CRMP1 significantly increases the odds of a child having a higher Autism Diagnostic Observation Schedule (ADOS) severity score (OR 2.3; 95% CI: 1.358–3.987, <i style="box-sizing: inherit;">p</i> = 0.0021). </p><p style="box-sizing: inherit; margin: 0px 0px 28px; overflow-wrap: break-word; padding: 0px;">This is the first report that uses machine learning subgroup discovery to identify with 100% accuracy MAR ASD-specific patterns as potential biomarkers of risk for a subset of up to 18% of ASD cases in this study population.</p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi3ipDoh_cDIp36ozIKxoJpFMggHpZ3pumUWm92jRtgs8tDCGEqM8PL6nTkKp4PoBCTAA6nBAKMrVwm4_mkZkxTojOCiGptMlVTDETXv-8rS1i2U1Bl7iDz628AYjOZ_hJDXwuQ/s1337/antibody+cluster.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="1312" data-original-width="1337" height="486" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi3ipDoh_cDIp36ozIKxoJpFMggHpZ3pumUWm92jRtgs8tDCGEqM8PL6nTkKp4PoBCTAA6nBAKMrVwm4_mkZkxTojOCiGptMlVTDETXv-8rS1i2U1Bl7iDz628AYjOZ_hJDXwuQ/w496-h486/antibody+cluster.JPG" width="496" /></a></div><br /><p style="box-sizing: inherit; margin: 0px 0px 28px; overflow-wrap: break-word; padding: 0px;"><br /></p><p style="box-sizing: inherit; margin: 0px 0px 28px; overflow-wrap: break-word; padding: 0px;"><br /></p></div></div></section></div>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-48522956698566612372020-11-23T15:23:00.002-06:002020-11-23T15:23:19.492-06:00Cannabis Epilepsy Trivia <p><b><u><span style="font-size: large;">Cannabis Trivia </span></u></b></p><p><span style="background-color: white; color: #050505; font-family: system-ui, -apple-system, system-ui, ".SFNSText-Regular", sans-serif; font-size: 15px;">CBD has been in the news as a treatment for many conditions epilepsy. </span><span style="background-color: white; color: #050505; font-family: system-ui, -apple-system, system-ui, ".SFNSText-Regular", sans-serif; font-size: 15px;">It was widely used for millennia by Indian "Arabian" and Persian medical traditions.</span></p><p><span style="background-color: white; color: #050505; font-family: system-ui, -apple-system, system-ui, ".SFNSText-Regular", sans-serif; font-size: 15px;">Q: When was cannabis first described in WESTERN medical literature as a TETANUS treatment</span><span style="background-color: white; color: #050505; font-family: system-ui, -apple-system, system-ui, ".SFNSText-Regular", sans-serif; font-size: 15px;">?</span></p><p>A: 1839</p><p><br /></p><div class="separator" style="clear: both; text-align: center;"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592602/bin/brforeignmedrev70073-0231.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="800" data-original-width="472" src="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592602/bin/brforeignmedrev70073-0231.jpg" /></a></div><p></p><p><br /></p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592602/pdf/brforeignmedrev70073-0231.pdf">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592602/pdf/brforeignmedrev70073-0231.pdf</a></p>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-64446051469351691212020-09-19T23:47:00.009-05:002020-09-19T23:57:33.518-05:00Medication Use ADD ADHD and Risk of Motor Vehicle Crashes<p><i> Is there a relationship between medication use and a LOWER risk of accidents? </i></p><p><i>Yes. </i></p><p><i>Short term? Yes.</i></p><p><i>Long-term? Yes.</i></p><p><i>Men? Yes.</i></p><p><i>Women? Yes. </i></p><p><i>Please take your medicines. </i></p><p><br /></p><h1 class="heading-title" style="background-color: white; box-sizing: inherit; clear: both; color: #212121; font-family: Merriweather, Georgia, Cambria, "Times New Roman", Times, serif; font-size: 2.6rem; line-height: 1.4; margin: 0px 0px 1.6rem; overflow-wrap: break-word;"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539840/" target="_blank">Association Between Medication Use for Attention-Deficit/Hyperactivity Disorder and Risk of Motor Vehicle Crashes</a></h1><div><br /></div><div><div class="sec sec-first" id="ab-yoi170020-1" style="background-color: white; clear: both; font-family: "Times New Roman", stixgeneral, serif; font-size: 15.9991px;"><h3 id="ab-yoi170020-1title" style="color: #724128; font-family: arial, helvetica, clean, sans-serif; font-size: 1em; font-weight: normal; line-height: 1.25em; margin: 1.2856em 0px 0.6428em;">Question</h3><p class="p p-first-last" id="__p15" style="margin: 0.6923em 0px;">Is the use of attention-deficit/hyperactivity disorder medication associated with a reduced risk of motor vehicle crashes in patients with the disorder?</p></div><div class="sec" id="ab-yoi170020-2" style="background-color: white; clear: both; font-family: "Times New Roman", stixgeneral, serif; font-size: 15.9991px;"><h3 id="ab-yoi170020-2title" style="color: #724128; font-family: arial, helvetica, clean, sans-serif; font-size: 1em; font-weight: normal; line-height: 1.25em; margin: 1.2856em 0px 0.6428em;">Findings</h3><p class="p p-first-last" id="__p16" style="margin: 0.6923em 0px;">In a national cohort study of 2 319 450 patients with attention-deficit/hyperactivity disorder, the use of medication for the disorder was associated with a significant reduction in the risk of motor vehicle crashes in male and female patients.</p></div><div class="sec sec-last" id="ab-yoi170020-3" style="background-color: white; clear: both; font-family: "Times New Roman", stixgeneral, serif; font-size: 15.9991px;"><h3 id="ab-yoi170020-3title" style="color: #724128; font-family: arial, helvetica, clean, sans-serif; font-size: 1em; font-weight: normal; line-height: 1.25em; margin: 1.2856em 0px 0.6428em;">Meaning</h3><p class="p p-first-last" id="__p17" style="margin: 0.6923em 0px;">Attention-deficit/hyperactivity disorder medication use may lower the risk of motor vehicle crashes, a prevalent and preventable cause of mortality and morbidity among patients with the disorder.</p></div></div>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-13518224011554725842020-09-19T23:41:00.000-05:002020-09-19T23:41:03.445-05:00ADHD & Accidents Crashes Violations Suspensions in Motor Vehicles - New Data<p><i><span style="font-size: medium;"> Do teens with ADHD have more accidents? More Moving Violations?</span></i></p><p><i><span style="font-size: medium;">Yes. For Years,</span></i></p><p><br /></p><h1 class="content-title" style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 1.5384em; font-weight: normal; line-height: 1.35em; margin: 1em 0px 0.5em;"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6564068/" target="_blank">Traffic Crashes, Violations, and Suspensions Among Young Drivers With ADHD</a></h1><h1 class="content-title" style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 1.5384em; font-weight: normal; line-height: 1.35em; margin: 1em 0px 0.5em;"><img alt="Accidents and Moving Violations in ADHD (purple) vs Control (orange)" border="0" data-original-height="1834" data-original-width="1224" height="400" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhGQsGyN8dG6PT7g1u348v3cXTWzltYOeKtoEGJBVchq4RZUum-BOKaiy2QOf-JPWu_lVgZNbH9yIDZNKxMSb5GIPiTXwc-Xtu21JtW_hlA-wlRJZ6pj7CCmiNYQP0wuP0-AccZ/w268-h400/Screen+Shot+2020-09-19+at+11.34.44+PM.png" style="color: #212121; font-family: system-ui, -apple-system, "Segoe UI", Roboto, Oxygen, Ubuntu, Cantarell, "Fira Sans", "Droid Sans", "Helvetica Neue", sans-serif; font-size: 16px;" title="DO teens, young adults witt ADHD have more accidents?" width="268" /><a class="affpopup" co-class="co-affbox" co-rid="_co_idm140100835510192" href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Curry%20AE%5BAuthor%5D&cauthor=true&cauthor_uid=31110164" style="color: #642a8f; font-size: 13.4792px; white-space: nowrap;">Allison E. Curry</a><span style="font-size: 13.4792px;">, PhD, MPH,</span><span style="font-size: 0.8461em; line-height: 1.6363em; position: relative; top: -0.5em; vertical-align: baseline;"><img alt="corresponding author" src="https://www.ncbi.nlm.nih.gov/corehtml/pmc/pmcgifs/corrauth.gif" style="border: 0px; max-width: 100%;" /></span><span style="font-size: 0.8461em; line-height: 1.6363em; position: relative; top: -0.5em; vertical-align: baseline;">a,</span><span style="font-size: 0.8461em; line-height: 1.6363em; position: relative; top: -0.5em; vertical-align: baseline;">b</span><span style="font-size: 13.4792px;"> </span><a class="affpopup" co-class="co-affbox" co-rid="_co_idm140100772959760" href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Yerys%20BE%5BAuthor%5D&cauthor=true&cauthor_uid=31110164" style="color: #642a8f; font-size: 13.4792px; white-space: nowrap;">Benjamin E. Yerys</a><span style="font-size: 13.4792px;">, PhD,</span><span style="font-size: 0.8461em; line-height: 1.6363em; position: relative; top: -0.5em; vertical-align: baseline;">c,</span><span style="font-size: 0.8461em; line-height: 1.6363em; position: relative; top: -0.5em; vertical-align: baseline;">d</span><span style="font-size: 13.4792px;"> </span><a class="affpopup" co-class="co-affbox" co-rid="_co_idm140100794801232" href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Metzger%20KB%5BAuthor%5D&cauthor=true&cauthor_uid=31110164" style="color: #642a8f; font-size: 13.4792px; white-space: nowrap;">Kristina B. Metzger</a><span style="font-size: 13.4792px;">, PhD, MPH,</span><span style="font-size: 0.8461em; line-height: 1.6363em; position: relative; top: -0.5em; vertical-align: baseline;">a</span><span style="font-size: 13.4792px;"> </span><a class="affpopup" co-class="co-affbox" co-rid="_co_idm140100796959872" href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Carey%20ME%5BAuthor%5D&cauthor=true&cauthor_uid=31110164" style="color: #642a8f; font-size: 13.4792px; white-space: nowrap;">Meghan E. Carey</a><span style="font-size: 13.4792px;">, MS,</span><span style="font-size: 0.8461em; line-height: 1.6363em; position: relative; top: -0.5em; vertical-align: baseline;">a</span><span style="font-size: 13.4792px;"> and </span><a class="affpopup" co-class="co-affbox" co-rid="_co_idm140100870108816" href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Power%20TJ%5BAuthor%5D&cauthor=true&cauthor_uid=31110164" style="color: #642a8f; font-size: 13.4792px; white-space: nowrap;">Thomas J. Power</a><span style="font-size: 13.4792px;">, PhD</span><span style="font-size: 0.8461em; line-height: 1.6363em; position: relative; top: -0.5em; vertical-align: baseline;">b,</span><span style="font-size: 0.8461em; line-height: 1.6363em; position: relative; top: -0.5em; vertical-align: baseline;">d</span></h1><h1 class="content-title" style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 1.5384em; font-weight: normal; line-height: 1.35em; margin: 1em 0px 0.5em;">Abstract</h1><div><div class="abstract-content selected" id="enc-abstract" style="background-color: white; box-sizing: inherit; clear: left;"><p style="box-sizing: inherit; clear: right; color: #212121; float: right; font-family: system-ui, -apple-system, "Segoe UI", Roboto, Oxygen, Ubuntu, Cantarell, "Fira Sans", "Droid Sans", "Helvetica Neue", sans-serif; font-size: 16px; line-height: 1.5; margin-bottom: 1em; margin-left: 1em; margin-top: 1.2rem;"><strong class="sub-title" style="box-sizing: inherit;">Methods: </strong>We identified patients of New Jersey primary care locations of the Children's Hospital of Philadelphia who were born in 1987-1997, were New Jersey residents, had their last primary care visit at age ≥12 years, and acquired a driver's license (<i style="box-sizing: inherit;">N</i> = 14 936). Electronic health records were linked to New Jersey's licensing, crash, and violation databases. ADHD diagnosis was based on <i style="box-sizing: inherit;">International Classification of Diseases, Ninth Revision, Clinical Modification</i> diagnostic codes. We calculated monthly per-driver rates of crashes (at fault, alcohol related, nighttime, and with peers), violations, and suspensions. Adjusted rate ratios were estimated by using repeated-measures Poisson regression.</p><p style="box-sizing: inherit; color: #212121; font-family: system-ui, -apple-system, "Segoe UI", Roboto, Oxygen, Ubuntu, Cantarell, "Fira Sans", "Droid Sans", "Helvetica Neue", sans-serif; font-size: 16px; line-height: 1.5; margin: 1.2rem 0px;"><strong class="sub-title" style="box-sizing: inherit;">Objectives: </strong>To compare monthly rates of specific types of crashes, violations, and license suspensions over the first years of licensure for drivers with and without attention-deficit/hyperactivity disorder (ADHD).</p><p style="box-sizing: inherit; color: #212121; font-family: system-ui, -apple-system, "Segoe UI", Roboto, Oxygen, Ubuntu, Cantarell, "Fira Sans", "Droid Sans", "Helvetica Neue", sans-serif; font-size: 16px; line-height: 1.5; margin: 1.2rem 0px;"><strong class="sub-title" style="box-sizing: inherit;">Results: </strong>Crash rates were higher for drivers with ADHD regardless of licensing age and, in particular, during the first month of licensure (adjusted rate ratio: 1.62 [95% confidence interval: 1.18-2.23]). They also experienced higher rates of specific crash types: their 4-year rate of alcohol-related crashes was 2.1 times that of drivers without ADHD. Finally, drivers with ADHD had higher rates of moving violations (for speeding, seat belt nonuse, and electronic equipment use) and suspensions. In the first year of driving, the rate of alcohol and/or drug violations was 3.6 times higher for adolescents with ADHD.</p><p style="box-sizing: inherit; color: #212121; font-family: system-ui, -apple-system, "Segoe UI", Roboto, Oxygen, Ubuntu, Cantarell, "Fira Sans", "Droid Sans", "Helvetica Neue", sans-serif; font-size: 16px; line-height: 1.5; margin: 1.2rem 0px;"><strong class="sub-title" style="box-sizing: inherit;">Conclusions: </strong>Adolescents with ADHD are at particularly high crash risk in their initial months of licensure, and engagement in preventable risky driving behaviors may contribute to this elevated risk. Comprehensive preventive approaches that extend beyond current recommendations are critically needed.</p><p style="box-sizing: inherit; color: #212121; font-family: system-ui, -apple-system, "Segoe UI", Roboto, Oxygen, Ubuntu, Cantarell, "Fira Sans", "Droid Sans", "Helvetica Neue", sans-serif; font-size: 16px; line-height: 1.5; margin: 1.2rem 0px;"><br /></p><div class="separator" style="clear: both; text-align: center;"><br /></div><br /><br /><p></p><p style="box-sizing: inherit; line-height: 1.5; margin: 1.2rem 0px;"><span style="color: #212121; font-family: system-ui, -apple-system, Segoe UI, Roboto, Oxygen, Ubuntu, Cantarell, Fira Sans, Droid Sans, Helvetica Neue, sans-serif;">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6564068/figure/fig2/?report=objectonly</span></p></div></div><div><br /></div>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-6808970568022429842020-08-04T18:31:00.006-05:002020-08-04T18:31:43.164-05:00Central Auditory Processing Disorder - CAPD Teaching Suggestions<p>Parents can use these at home too.</p><p>"Suggestions for Successful Management of Students with Central Auditory Processing Disorder (CAPD): Tips for the Teacher"</p><p>The student with a central auditory processing disorder (CAPD) will respond in a variety of ways to changes within their environment and instructional program. Management suggestions identified for a student with a CAPD should be based on the student’s individual profile of auditory processing strengths and weaknesses. Suggestions in this listing are in the areas of attention, preferential seating, instructions, preview and review, time, classroom adaptations, self-advocacy, and organizational strategies. The audiologist will select those strategies most appropriate for the student’s CAP profile."</p><p>Full PDF here </p><p><a href="http://www.iag-online.org/resources/New-Items-2e/CAPD-TipsForTeachers.pdf">http://www.iag-online.org/resources/New-Items-2e/CAPD-TipsForTeachers.pdf</a></p><p><strong><u><br /></u></strong></p><p><strong><u>CAPD - Central Auditory Processing Disorder</u></strong>
- Strategies <o:p></o:p></p>
<p><b><u>Attention <o:p></o:p></u></b></p>
<p>• <span style="mso-spacerun: yes;"> </span>Gain bi-sensory attention. Auditory
processing is maximized when the same information is received simultaneously
through different modalities. Therefore, it is important to gain the student’s
visual as well as auditory attention before speaking with him or her. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Speak at eye level. Whenever
possible, speak at the student’s eye level, get close to the student, and face
the student to provide clear visual and auditory information. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Use cueing. It may be beneficial to
work out a cueing system to help students become aware of times when they are
not paying attention. These “pretuning” techniques help to focus the student’s
attention on the subject coming up. Use words such as “listen,” “ready,” and
“remember this one.” <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Assign peer partners. Assign a peer
partner to the student with a CAPD. The peer partner can assist the student
with a CAPD in activities such as paying attention, getting assignments listed,
participating in small group projects, and tuning in for key information. Peer
tutoring may also be a part of the buddy system if appropriate. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Mark transitions between
activities. Students with auditory processing difficulties often need more time
to make transitions. Therefore, it is helpful and important to mark transitions
between activities by clearly identifying the new activity by naming and
explaining the sequence of steps needed to accomplish the task. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Review and transition. Clearly
closing an activity may be accomplished by briefly summarizing what the student
should have learned and/or completed before transitioning to the next activity.
<o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Provide notetaking assistance.
Because it is difficult to watch the teacher and take notes simultaneously, it
may be helpful for the student to be able to get a copy of another student’s
notes, to get a copy of the teacher’s notes, to have a study guide, and/or be
able to record the lesson for future reference and study. <o:p></o:p></p>
<p><b><u>Flexible Preferential Seating <o:p></o:p></u></b></p>
<p>• <span style="mso-spacerun: yes;"> </span>Provide preferential seating
distance. Seat the student near the primary sound source (e.g., teacher, television,
computer, center activity area). A distance of three-four feet is the best, but
a distance up to six-eight feet should be adequate. This allows the student to
derive maximum benefit from both auditory and visual information cues. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Avoid seating near noise sources.
Seat the student away from competing or distracting noise sources (e.g.,
external noise sources, bathroom area, telecommunications equipment, aquarium).
Seating away from windows and doorways also will reduce possible sources of distraction.
<o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Provide better ear option. Seat the
student so that the better ear, if indicated, is directed toward the primary
sound source. (The audiologist will provide this recommendation if
appropriate.) <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Allow flexible preferential seating
options. Allow flexibility in seating to continuously achieve the preferential
seating advantage. This enables the student to attend and actively participate
as the classroom activities and the teacher or other primary sound source
change location. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Provide quiet study/work area.
Provide the student with a “private” or isolated area, such as a study carrel,
for individual seatwork, testing, or tutoring. This helps to minimize the
student’s problems in foreground/ background discrimination. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Use daily routines. Use daily
routines or schedules to help keep the student focused and organized. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Use earplugs. If their use is
recommended, allow the student to use earplugs or earmuffs during individual
seatwork time to help tune out distractions. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span><span style="mso-spacerun: yes;"> </span>FM amplification. Use a personal or sound
field FM system to improve access to auditory information, if this is indicated
by the student’s CAP profile. Students with difficulty hearing in noise,
integrating information, or organizing information may benefit from FM amplification.
An audiologist should make the recommendation for an FM system. The teacher(s)
will receive an in-service on the use of the FM system. 66 Instructions <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Speak in a clear, well-modulated
voice. Speak distinctly, at a comfortably loud level, and at a rate the student
can follow easily. Vary loudness to increase the student’s attention. Remember
not to overexaggerate your speech. Emphasize important information using
intonation and stress. Repeat important words when necessary. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Use natural gestures. Use natural
gestures that enhance the message. Avoid extraneous gestures and excessive
movement while delivering the message if this appears to distract the student. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Reduce distractions. Avoid
extraneous noises and visual distractions, especially when giving instructions
and teaching new concepts. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Alert the student. Before giving
instructions, stand close to the student, call the student’s name, and gently
tap the student’s shoulder, or use another cue to make sure you have the
student’s attention. Using the student’s name during teaching time also will
help to maintain attention. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Reduce motor activities during
instruction time. Reducing motor activities during verbal presentations is
helpful for some students with a CAPD, especially if the student has an
integration deficit. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Define purpose. State the purpose
of each activity clearly and directly before introducing the specific
instructions for task completion. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Give age and ability-appropriate
directions. Give direct and uncomplicated directions. Use age-appropriate
vocabulary that clarifies the logical, time-ordered sequence (e.g., first,
second, last). <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Repeat direction and allow ample
response time. It may be necessary to repeat each step of the instruction and
allow time between each step for the student to process the information. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Provide examples. Work on an
example together and leave the example on display. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Use modeling. Use modeling to
provide a clear demonstration of student performance expectations. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Identify key words. Emphasize key
words when speaking or writing, especially when presenting new information. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Give written and verbal
instructions. Provide both written and verbal instructions to aid the student
in following directions and completing tasks. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>List the steps. To help the student
learn multi-step sequences, list the steps on a reference card. As the student
becomes more familiar with the sequence, steps in the written directions may be
omitted gradually and systematically until the student is able to complete the
sequence automatically without referring to the written cues. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Encourage the student to ask for
clarification. Encourage the student to ask questions for clarification of
information. It may be necessary to rephrase the information to ensure that the
student with a CAPD is able to comprehend. Also, some students with a CAPD have
a language deficit and may not be familiar with key words. By substituting
words and simplifying the grammar, the intended meaning may be conveyed and
understood more easily. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Repeat or paraphrase. Have the
student repeat the content of the instructions to provide the comprehension
feedback. This technique allows the teacher to see which parts of the
instruction need to be corrected or repeated. Ask for verbal accounts rather
than a “yes” or “no” response. Reinforce listening for meaning rather than
exact repetition. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Give positive feedback. It is
important that students receive positive feedback to ensure understanding of
the message or instruction correctly. Feedback is important even if the student
understood only a portion of the message. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Boost self-confidence. Many
students with a CAPD lack of self-confidence due to comparisons made by
themselves or others about their performance. Reinforcing all work performed
successfully will help to alleviate this problem. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Check instruction comprehension.
Check the student’s work after the first few items to ensure that the student
understood and retained the instructions. The teacher should watch for signs of
inattention, decreased concentration, or understanding. Periodic comprehension
checks (e.g., paraphrasing instructions, main idea, key points) are helpful to
keep the student on task. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Allow subvocalization. To help with
reading comprehension, the student could be allowed to subvocalize while
reading until such time as this is unnecessary. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Allow reauditorization. Some
students have a need to reauditorize information as they formulate their
response. This strategy also strengthens the memory trace. 67 Preview and
Review <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Review, preview, and summarize
class lessons. For all class lessons, review previous material, preview
material to be presented, and help students summarize the material presented.
Discuss new and previously introduced vocabulary words and concepts. Whenever
possible, relate new information to the student’s previous experiences and
environment. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Provide pre-teaching materials and
assignments. Provide preassigned readings and home assignments to help
introduce new concepts and topics. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Avoid divided attention. Avoid asking
students with a CAPD to divide their attention between listening and taking
notes at the same time. Allow students to tape record lessons or provide
students with a detailed outline of the information presented in the class
lesson. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Review and orient. Provide a short
review statement about the topic(s) to be discussed to orient the student.
Write a brief outline and list key vocabulary on the board or an overhead
projector. Provide the student with a copy of the outline and key vocabulary to
use in following the discussion and for review. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Frequently summarize key points.
Repeat and summarize key points frequently. Emphasize key vocabulary words
during the discussion. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Give salient clues. Give salient
clues to identify and emphasize important information (e.g., “This is
important,” “The main points are…,” “This could be a test question.”). <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Use verbal review strategies. Use
verbal review strategies to ask questions periodically about the material being
presented. This is a helpful topic maintenance strategy. Verbal review
questions should include language required for description, explanation,
exemplification, comparison, and relating real events to abstract principles. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Give individual attention. Students
with a CAPD often need individual attention. Inform resource personnel and
parents of planned vocabulary and curriculum topics to be covered in the
classroom to allow opportunity for pre-teaching as a supplement to classroom
activities. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Reference important pages. Refer
students to important textbook pages for less review and preview. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Encourage class participation.
Encourage participation in expressive language activities related to each
lesson. Reading is especially important since information and knowledge gained
through reading help compensate for what may be missed because of auditory
difficulties. Time <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Avoid fatigue. Students with a CAPD
often become fatigued more easily than their peers. It is often difficult for
the student to attend because of the effort required to keep up and compete in
classroom activities. To minimize fatigue, consider the following suggestions.
- Give several short classroom activities instead of one long activity. -
Provide short periods of instruction with breaks so the student can move around
if needed. - Alternate activities requiring greater auditory processing
requirements with those that are less demanding. - Avoid higher-level auditory
tasks when the student is already fatigued. (Consider presenting high-auditory
content information during the morning.) <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Allow extended time. Students with
a CAPD should be given adequate time to comprehend and complete tasks. Avoid
giving penalties for not completing assignments in the prescribed classroom
time. Whenever possible, give students fewer items to complete in the amount of
classroom time available or give them additional time in the resource room to
complete the assignment. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Give adequate response time. It may
be necessary to allow students with a CAPD more time to formulate responses to
verbal questions, especially questions that include comparisons,
generalizations, and explanations requiring lengthier and more complex language
organization. Classroom Adaptations <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Record instructions. Class lessons
or instructions can be recorded so that the student can listen to and review
the material later. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span><span style="mso-spacerun: yes;"> </span>Sound tune the classroom. Acoustical
modifications may be implemented to create a positive acoustical listening and
learning environment (e.g., carpeting, drapes, sound absorbing materials).<o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Arrange classroom. Structure the
classroom to reduce background noise, reverberation, and distractions. Noise
interferes with the reception of auditory information and distracts the
listener from the complex task of processing (e.g., organizing and
interpreting) information. Special areas for small group instruction that are
relatively quiet and distraction-free are helpful for many students. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Avoid open classrooms. Avoid open
classroom settings for students with a CAPD. In these settings, reduce
distractions by using sound barriers (e.g., bookshelves, flannel boards) and
other modifications to improve the listening environment. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Close windows and doors. Keep doors
and windows closed to reduce external noise entering the classroom. <o:p></o:p></p>
<p><b><u>Self Advocacy <o:p></o:p></u></b></p>
<p>• <span style="mso-spacerun: yes;"> </span>Encourage self-monitoring. Encourage
the student to self-monitor the listening environment and identify any problems
that may be interfering with the learning process. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Encourage self-advocacy. Encourage
the student to self-regulate by using strategies to modify conditions and
situations that may compromise effective learning. This will assist the student
in learning self-regulation strategies and becoming an effective manager of his
listening and learning environment. <o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Suggest counseling. If necessary,
the student should be referred for counseling for social/emotional concerns as
part of the management plan. The student (and parents) needs to understand the
nature of the CAPD and why it is essential to develop compensatory strategies. <o:p></o:p></p>
<p><b><u>Organizational Strategies <o:p></o:p></u></b></p>
<p>• <span style="mso-spacerun: yes;"> </span>Encourage the use of agenda book or
other organizers. Encourage the student to consistently use an agenda book (or
other organizer or calendar) to ensure that assignments, upcoming events, and
other important class information are recorded.<o:p></o:p></p>
<p>• <span style="mso-spacerun: yes;"> </span>Clearly present organizational
expectations. Ensure that the student understands specific organizational
expectations for the classroom (e.g., where to place homework, use of folders,
required classroom tools). Use cue cards as reminders.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p><br />Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-87647507051404230392020-05-11T21:04:00.000-05:002020-05-11T21:04:03.029-05:00Vitamin D and Covid-19<a href="https://www.sciencedaily.com/releases/2020/05/200507121353.htm" target="_blank">Covid-19 Prevention with Vitamin D</a><div><br /></div><div><h1 class="headline" id="headline" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0); -webkit-text-size-adjust: 100%; border-bottom-left-radius: 0px !important; border-bottom-right-radius: 0px !important; border-top-left-radius: 0px !important; border-top-right-radius: 0px !important; box-sizing: border-box; color: #004276; font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 24px; font-weight: 500; line-height: 1.1; margin: 0px;">Vitamin D levels appear to play role in COVID-19 mortality rates</h1><h2 class="subtitle" id="subtitle" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0); -webkit-text-size-adjust: 100%; border-bottom-left-radius: 0px !important; border-bottom-right-radius: 0px !important; border-top-left-radius: 0px !important; border-top-right-radius: 0px !important; box-sizing: border-box; caret-color: rgb(51, 51, 51); color: #333333; font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 18px; font-weight: 500; line-height: 1.1; margin: 5px 0px 0px;">Patients with severe deficiency are twice as likely to experience major complications</h2><dl class="dl-horizontal dl-custom" style="-webkit-tap-highlight-color: rgba(0, 0, 0, 0); -webkit-text-size-adjust: 100%; border-bottom-left-radius: 0px !important; border-bottom-right-radius: 0px !important; border-top-left-radius: 0px !important; border-top-right-radius: 0px !important; box-sizing: border-box; caret-color: rgb(51, 51, 51); color: #333333; font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 14px; margin: 20px 0px 0px;"><dt style="border-bottom-left-radius: 0px !important; border-bottom-right-radius: 0px !important; border-top-left-radius: 0px !important; border-top-right-radius: 0px !important; box-sizing: border-box; clear: left; float: left; font-style: italic; line-height: 1.42857143; overflow: hidden; padding-bottom: 5px; text-align: right; text-overflow: ellipsis; white-space: nowrap; width: 70px;">Date:</dt><dd id="date_posted" style="border-bottom-left-radius: 0px !important; border-bottom-right-radius: 0px !important; border-top-left-radius: 0px !important; border-top-right-radius: 0px !important; box-sizing: border-box; line-height: 1.42857143; margin-left: 90px; padding-bottom: 5px;">May 7, 2020</dd><dt style="border-bottom-left-radius: 0px !important; border-bottom-right-radius: 0px !important; border-top-left-radius: 0px !important; border-top-right-radius: 0px !important; box-sizing: border-box; clear: left; float: left; font-style: italic; line-height: 1.42857143; overflow: hidden; padding-bottom: 5px; text-align: right; text-overflow: ellipsis; white-space: nowrap; width: 70px;">Source:</dt><dd id="source" style="border-bottom-left-radius: 0px !important; border-bottom-right-radius: 0px !important; border-top-left-radius: 0px !important; border-top-right-radius: 0px !important; box-sizing: border-box; line-height: 1.42857143; margin-left: 90px; padding-bottom: 5px;">Northwestern University</dd><dt style="border-bottom-left-radius: 0px !important; border-bottom-right-radius: 0px !important; border-top-left-radius: 0px !important; border-top-right-radius: 0px !important; box-sizing: border-box; clear: left; float: left; font-style: italic; line-height: 1.42857143; overflow: hidden; padding-bottom: 5px; text-align: right; text-overflow: ellipsis; white-space: nowrap; width: 70px;">Summary:</dt><dd id="abstract" style="border-bottom-left-radius: 0px !important; border-bottom-right-radius: 0px !important; border-top-left-radius: 0px !important; border-top-right-radius: 0px !important; box-sizing: border-box; line-height: 1.42857143; margin-bottom: 15px; margin-left: 90px; padding-bottom: 5px;">Researchers analyzed patient data from 10 countries. The team found a correlation between low vitamin D levels and hyperactive immune systems. Vitamin D strengths innate immunity and prevents overactive immune responses. The finding could explain several mysteries, including why children are unlikely to die from COVID-19.</dd></dl></div>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-82410630331619519262020-04-23T22:35:00.002-05:002020-04-23T22:35:46.869-05:00Covid-19 & Congenital Muscular Dystrophy - Preparation and Airway Clearance<div class="separator" style="clear: both; text-align: center;">
<i><span style="font-size: large;">Check with your pulmonologist if this advice is best for you / your child. I am just a pediatric neurologist. Please call them. JR</span></i></div>
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<br />Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-16135171546522601542020-04-21T17:01:00.003-05:002020-04-22T19:04:39.154-05:00Autism, CBD-Low THC Presentation <div class="separator" style="clear: both; text-align: center;">
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<i>Thank you to Compassionate Cultivation for coordinating the early AM Zoom meeting. FYI ...Im tired. JR</i><br />
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<span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">Autism and CBD </span></span></div>
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<b><u><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;"></span></span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> Overview</span></u></b></div>
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<ul>
<li style="font-family: Calibri, sans-serif; font-size: 12pt;"><b style="font-size: 12pt;"><o:p><span style="font-size: small;"><span style="font-weight: normal;"><i>I am discussing a complementary treatment</i></span></span></o:p></b></li>
<li style="font-family: Calibri, sans-serif; font-size: 12pt;"><span style="font-family: "calibri" , sans-serif;"><i>The </i></span><i style="font-size: 12pt;">Low THC CBD program (TCUP) is NOT recreational cannabis.</i></li>
<li style="font-family: Calibri, sans-serif; font-size: 12pt;"><i style="font-size: 12pt;">I am treating a diverse population of neurologically complex individuals. </i></li>
<li style="font-family: Calibri, sans-serif; font-size: 12pt;"><span style="font-family: "calibri" , sans-serif;"><i>People</i></span><i style="font-size: 12pt;"> with </i><span style="font-family: "calibri" , sans-serif;"><i>autism</i></span><i style="font-size: 12pt;"> have </i><span style="font-family: "calibri" , sans-serif;"><i>significant</i></span><i style="font-size: 12pt;"> problems that </i><span style="font-family: "calibri" , sans-serif;"><i>impact</i></span><i style="font-size: 12pt;"> their lives AND the lives of </i><span style="font-family: "calibri" , sans-serif;"><i>others</i></span><i style="font-size: 12pt;">. </i></li>
<li style="font-family: Calibri, sans-serif; font-size: 12pt;"><i>Cannabinoids have a biologic basis for efficacy</i></li>
<li><i style="font-family: Calibri, sans-serif; font-size: 12pt;">Clinical data for </i><span style="font-family: "calibri" , sans-serif;"><i>indication, risks is emerging but exists.</i></span></li>
<li><span style="font-family: "calibri" , sans-serif;"><i>Link to a selection of PEER-REVIEWED articles (pro and con)</i></span></li>
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<b><u>What is a Complementary Treatment? </u></b><b><u>Added therapy BEYOND Standard treatment.</u></b></div>
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<b><u><br /></u></b></div>
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<tr><td style="text-align: center;"><a href="https://media.springernature.com/full/springer-static/image/art%3A10.1007%2Fs13311-015-0371-9/MediaObjects/13311_2015_371_Fig1_HTML.gif" imageanchor="1" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto;"><img border="0" data-original-height="524" data-original-width="609" height="274" src="https://media.springernature.com/full/springer-static/image/art%3A10.1007%2Fs13311-015-0371-9/MediaObjects/13311_2015_371_Fig1_HTML.gif" width="320" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">AUTISM and the ENDO Cannabinoid System - see below</td></tr>
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<b><u> Caveats - Complementary therapies will:</u></b></div>
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<b><u><o:p></o:p></u></b><br /><b><u><o:p></o:p></u></b></div>
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<span style="color: black; font-family: "arial" , sans-serif;">(1)<span style="font-family: "times new roman"; font-stretch: normal; line-height: normal;"> </span></span><span dir="LTR"></span><span style="color: black; font-family: "arial" , sans-serif;">provide a <i>reasonable potential for therapeutic gain</i> and (2) do not unreasonably place the patient's medical condition at risk. <o:p></o:p></span></div>
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<span style="color: black; font-family: "arial" , sans-serif;"></span><br /><span style="color: black; font-family: "arial" , sans-serif;"></span></div>
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<span style="font-family: "times new roman" , serif;">(2)<span style="font-family: "times new roman"; font-stretch: normal; line-height: normal;"> </span></span><span dir="LTR"></span><span style="color: black; font-family: "arial" , sans-serif;"><u><b>... there is a professional obligation on physicians to:</b></u></span></div>
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<span style="color: black; font-family: "arial" , sans-serif;"><u><b> </b></u>(a) investigate, understand and assess whether the underlying therapeutic basis is designed to improve a patient's overall quality of life (even anecdotally and for limited a duration) and to </span></div>
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<span style="color: black; font-family: "arial" , sans-serif;"> (b) ensure that the therapy is not medically contraindicated</span><span style="font-family: "times new roman" , serif; font-size: 12px;"><o:p></o:p></span></div>
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<b><u>BACKGROUND</u></b></div>
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<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; background-color: white; clear: both; color: rgba(0, 0, 0, 0.847); cursor: text; direction: ltr; font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px; font-variant-ligatures: normal; margin: 0px; orphans: 2; overflow: visible; padding: 0px; position: relative; widows: 2;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{f1608cdc-aad0-41a4-b184-ddca2be03141}{202}" paraid="1420382022" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">Incidence of Autism in Children </span></span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</div>
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; background-color: white; clear: both; color: rgba(0, 0, 0, 0.847); cursor: text; direction: ltr; font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px; font-variant-ligatures: normal; margin: 0px; orphans: 2; overflow: visible; padding: 0px; position: relative; widows: 2;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{f1608cdc-aad0-41a4-b184-ddca2be03141}{208}" paraid="1458236098" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US"><br /></span></div>
<div class="Paragraph SCXW162450012 BCX0" paraeid="{f1608cdc-aad0-41a4-b184-ddca2be03141}{208}" paraid="1458236098" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">In March 2014, the Center for Disease Control released a new estimate for children with an autism spectrum disorder. According to the CDC, one in 68 children have ASD, which is a 30 percent increase over the previous estimate of one in 88. </span></div>
</div>
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; background-color: white; clear: both; color: rgba(0, 0, 0, 0.847); cursor: text; direction: ltr; font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px; font-variant-ligatures: normal; margin: 0px; orphans: 2; overflow: visible; padding: 0px; position: relative; widows: 2;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{f1608cdc-aad0-41a4-b184-ddca2be03141}{214}" paraid="1859773286" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<br /></div>
</div>
<div class="SCXW162450012 BCX0" style="-webkit-user-drag: none; background-color: white; color: rgba(0, 0, 0, 0.847); font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px; font-variant-ligatures: normal; margin: 0px; orphans: 2; padding: 0px; widows: 2;">
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; margin: 0px; overflow: visible; padding: 0px; position: relative;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{f1608cdc-aad0-41a4-b184-ddca2be03141}{218}" paraid="1289616936" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">Assuming there are approximately 7 million children in Texas (2016):</span></span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</div>
<div class="ListContainerWrapper SCXW162450012 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px; position: relative;">
<ul class="BulletListStyle1 SCXW162450012 BCX0" role="list" style="-webkit-user-drag: none; cursor: text; font-family: verdana; margin: 0px; overflow: visible; padding: 0px;">
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="1" data-font="Symbol" data-leveltext="" data-listid="1" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{f1608cdc-aad0-41a4-b184-ddca2be03141}{224}" paraid="1953707491" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">102,941 have autism</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="2" data-font="Symbol" data-leveltext="" data-listid="1" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{f1608cdc-aad0-41a4-b184-ddca2be03141}{231}" paraid="1930894672" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">14,700 have mild cognitive impairment</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="3" data-font="Symbol" data-leveltext="" data-listid="1" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{f1608cdc-aad0-41a4-b184-ddca2be03141}{238}" paraid="394550359" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">9,100 have</span><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US"> </span><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">moderate and severe cognitive impairment</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="4" data-font="Symbol" data-leveltext="" data-listid="1" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{f1608cdc-aad0-41a4-b184-ddca2be03141}{249}" paraid="2067278790" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">In comparison, about 70,000 children have epilepsy in Texas and about 14,000 have refractory epilepsy.</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
</ul>
</div>
</div>
<div class="SCXW162450012 BCX0" style="-webkit-user-drag: none; background-color: white; color: rgba(0, 0, 0, 0.847); font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px; font-variant-ligatures: normal; margin: 0px; orphans: 2; padding: 0px; widows: 2;">
<div class="ListContainerWrapper SCXW162450012 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px; position: relative;">
<ul class="BulletListStyle1 SCXW162450012 BCX0" role="list" style="-webkit-user-drag: none; cursor: text; font-family: verdana; margin: 0px; overflow: visible; padding: 0px;">
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="1" data-font="Symbol" data-leveltext="" data-listid="1" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{1}" paraid="445389482" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">Theoretically, about 77,000 Texas children have autism and insomnia. </span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
</ul>
</div>
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; margin: 0px; overflow: visible; padding: 0px; position: relative;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{8}" paraid="543690952" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<br /></div>
</div>
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; margin: 0px; overflow: visible; padding: 0px; position: relative;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{12}" paraid="515025461" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">Incidence of Insomnia in Children with autism, cognitive impairment</span></span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</div>
<div class="ListContainerWrapper SCXW162450012 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px; position: relative;">
<ul class="BulletListStyle1 SCXW162450012 BCX0" role="list" style="-webkit-user-drag: none; cursor: text; font-family: verdana; margin: 0px; overflow: visible; padding: 0px;">
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="2" data-font="Symbol" data-leveltext="" data-listid="2" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{18}" paraid="1400191084" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">Insomnia in children with ASD occurs across all cognitive levels, and the prevalence may be as high as 60–86%, which is two to three times greater than typically developing (TD) children [3, 7, 22–27].</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="3" data-font="Symbol" data-leveltext="" data-listid="2" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{25}" paraid="864095974" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">20% agitation.</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
</ul>
</div>
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<div class="SCXW162450012 BCX0" style="-webkit-user-drag: none; background-color: white; color: rgba(0, 0, 0, 0.847); font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px; font-variant-ligatures: normal; margin: 0px; orphans: 2; padding: 0px; widows: 2;">
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; margin: 0px; overflow: visible; padding: 0px; position: relative;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{32}" paraid="335113595" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"><br /></span></div>
<div class="SCXW162450012 BCX0" style="-webkit-user-drag: none; font-variant-ligatures: normal; margin: 0px; padding: 0px;">
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; margin: 0px; overflow: visible; padding: 0px; position: relative;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{159}" paraid="1480868367" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">Outcomes for insomnia in Children </span></span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</div>
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<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{32}" paraid="335113595" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"></span></div>
<div class="SCXW162450012 BCX0" style="-webkit-user-drag: none; font-variant-ligatures: normal; margin: 0px; padding: 0px;">
<div class="ListContainerWrapper SCXW162450012 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px; position: relative;">
<ul class="BulletListStyle1 SCXW162450012 BCX0" role="list" style="-webkit-user-drag: none; cursor: text; font-family: verdana; margin: 0px; overflow: visible; padding: 0px;">
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="1" data-font="Symbol" data-leveltext="" data-listid="4" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{169}" paraid="265376994" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">Accidents</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="2" data-font="Symbol" data-leveltext="" data-listid="4" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{176}" paraid="998616682" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">Elopement</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="3" data-font="Symbol" data-leveltext="" data-listid="4" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{183}" paraid="1921324496" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">Medicine side effects</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="4" data-font="Symbol" data-leveltext="" data-listid="4" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{190}" paraid="1621800384" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">Poor daytime functioning / adverse developmental outcome</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
</ul>
</div>
</div>
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{32}" paraid="335113595" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<br /></div>
</div>
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; margin: 0px; overflow: visible; padding: 0px; position: relative;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{36}" paraid="1373501402" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">What medicines </span></span><span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun ContextualSpellingAndGrammarErrorV2 SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; background-image: url("data:image/svg+xml; background-position: left bottom; background-repeat: repeat no-repeat; border-bottom-color: transparent; border-bottom-style: solid; border-bottom-width: 1px; margin: 0px; padding: 0px;">are FDA</span></span><span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">-approved for insomnia in children</span></span><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">? </span><span class="TextRun MacChromeBold SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 14pt; font-weight: bold; line-height: 23.7417px; margin: 0px; padding: 0px;" xml:lang="EN-US">None</span><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">.</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</div>
<div class="ListContainerWrapper SCXW162450012 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px; position: relative;">
<ul class="BulletListStyle1 SCXW162450012 BCX0" role="list" style="-webkit-user-drag: none; cursor: text; font-family: verdana; margin: 0px; overflow: visible; padding: 0px;">
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="1" data-font="Symbol" data-leveltext="" data-listid="3" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{52}" paraid="137895663" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">Medications such as benzodiazepines (</span><span class="NormalTextRun SpellingErrorV2 SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; background-image: url("data:image/svg+xml; background-position: left bottom; background-repeat: repeat no-repeat; border-bottom-color: transparent; border-bottom-style: solid; border-bottom-width: 1px; margin: 0px; padding: 0px;">e.g.valium</span><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">) and diphenhydramine (</span><span class="NormalTextRun SpellingErrorV2 SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; background-image: url("data:image/svg+xml; background-position: left bottom; background-repeat: repeat no-repeat; border-bottom-color: transparent; border-bottom-style: solid; border-bottom-width: 1px; margin: 0px; padding: 0px;">e.g</span><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;"> Benadryl) were shown to have paradoxical, excitatory or even SEIZURE-provoking response.</span></span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</li>
</ul>
</div>
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; margin: 0px; overflow: visible; padding: 0px; position: relative;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{59}" paraid="582499757" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<br /></div>
</div>
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; margin: 0px; overflow: visible; padding: 0px; position: relative;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{63}" paraid="354394749" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">What medicines are used? What are the side effects?</span></span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</div>
</div>
<div class="SCXW162450012 BCX0" style="-webkit-user-drag: none; background-color: white; color: rgba(0, 0, 0, 0.847); font-variant-ligatures: normal; margin: 0px; orphans: 2; padding: 0px; widows: 2;">
<div class="ListContainerWrapper SCXW162450012 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px; position: relative;">
<ul style="font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px;">
<li><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">Melatonin followed by α-agonists (</span><span class="NormalTextRun SpellingErrorV2 SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; background-image: url("data:image/svg+xml; background-position: left bottom; background-repeat: repeat no-repeat; border-bottom-color: transparent; border-bottom-style: solid; border-bottom-width: 1px; margin: 0px; padding: 0px;">e.g</span><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;"> clonidine)</span></span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></li>
<li><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;">Anti-Depressants (e.g.trazodone)</span></li>
<li><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;">Anti-Psychotics</span></li>
<li><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;">Anti-Convulsants</span></li>
<li><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">"In general pediatric insomnia, antihistamines are prescribed most commonly (n = 8367 [88.6%]), followed by antipsychotic agents (n = 465 [4.9%]), α-adrenergic receptor agonists (n = 399 [4.2%]), and selective serotonin reuptake inhibitors (n = 159 [0.1%]).”</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></li>
</ul>
<div>
<span style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif;"><span style="font-size: 14.666666984558105px;"><b><u>What about Commercial CBD Products?</u></b></span></span></div>
<ul style="font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px;">
<li><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">Safety</span></li>
<li><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">Reliability</span></li>
<li><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">Watch for pesticides, lead – other health problems</span></li>
</ul>
</div>
</div>
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; background-color: white; clear: both; color: rgba(0, 0, 0, 0.847); cursor: text; direction: ltr; font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px; font-variant-ligatures: normal; margin: 0px; orphans: 2; overflow: visible; padding: 0px; position: relative; widows: 2;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{102}" paraid="1183973549" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<br /></div>
</div>
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; background-color: white; clear: both; color: rgba(0, 0, 0, 0.847); cursor: text; direction: ltr; font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px; font-variant-ligatures: normal; margin: 0px; orphans: 2; overflow: visible; padding: 0px; position: relative; widows: 2;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{106}" paraid="603719652" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">Texas MCD – estimate of expenditures</span></span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
</div>
<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; background-color: white; clear: both; color: rgba(0, 0, 0, 0.847); cursor: text; direction: ltr; font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px; font-variant-ligatures: normal; margin: 0px; orphans: 2; overflow: visible; padding: 0px; position: relative; widows: 2;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{112}" paraid="2121429198" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">Costs</span></span><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">: ASD costs a family $60,000/year on average</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
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<div class="OutlineElement Ltr BCX0 SCXW162450012" style="-webkit-user-drag: none; background-color: white; clear: both; color: rgba(0, 0, 0, 0.847); cursor: text; direction: ltr; font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px; font-variant-ligatures: normal; margin: 0px; orphans: 2; overflow: visible; padding: 0px; position: relative; widows: 2;">
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{120}" paraid="1367843473" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; margin-left: 24px; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun MacChromeBold Underlined SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; text-decoration: underline;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;">What number of physician visits for insomnia? </span></span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559685":360,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
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<ul class="BulletListStyle1 SCXW162450012 BCX0" role="list" style="-webkit-user-drag: none; cursor: text; font-family: verdana; margin: 0px; overflow: visible; padding: 0px;">
<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="1" data-font="Symbol" data-leveltext="" data-listid="2" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 48px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{126}" paraid="235718071" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">The prevalence of sleep problems among typically developing children is as high as 25%.</span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559685":1080,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
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<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="2" data-font="Symbol" data-leveltext="" data-listid="2" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt; margin: 0px 0px 0px 48px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{133}" paraid="1920853951" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">In one study of </span><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US">outpatient</span><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US"> general pediatric visits “potentially sleep-related medications were prescribed for 6.1% of children (n = 9441)”. </span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559685":1080,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"> </span></div>
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<li aria-setsize="-1" class="OutlineElement Ltr BCX0 SCXW162450012" data-aria-level="1" data-aria-posinset="3" data-font="Symbol" data-leveltext="" data-listid="2" role="listitem" style="-webkit-user-drag: none; clear: both; cursor: text; direction: ltr; display: block; font-family: Calibri, Calibri_MSFontService, sans-serif; margin: 0px 0px 0px 24px; overflow: visible; padding: 0px; position: relative; vertical-align: baseline;"><div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{148}" paraid="1600412089" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; font-size: 11pt; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
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<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{148}" paraid="1600412089" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; font-size: 11pt; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"><br /></span></div>
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{148}" paraid="1600412089" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; font-size: 11pt; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"><br /></span></div>
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{148}" paraid="1600412089" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; line-height: 19.425px; margin: 0px; padding: 0px;"><b><u><span style="font-size: large;"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604173/" target="_blank">The Endocannabanoid System in Autism</a> </span><span style="font-size: 11pt;">Click For the article</span></u></b></span></div>
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<span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"><b><u><br /></u></b></span></div>
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<span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; line-height: 19.425px; margin: 0px; padding: 0px;"><b><u><br /></u></b></span></div>
<div class="Paragraph SCXW162450012 BCX0" paraeid="{750f2023-095b-4e4f-9d92-bb5482cd473b}{148}" paraid="1600412089" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;">
<span class="EOP SCXW162450012 BCX0" data-ccp-props="{"134233279":true,"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; line-height: 19.425px; margin: 0px; padding: 0px;"><b><u><span style="font-size: large;"><br /></span></u></b></span></div>
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<div class="Paragraph SCXW162450012 BCX0" lang="EN-US" paraeid="{1918d86a-b026-41ab-a666-89d002ca515b}{43}" paraid="1332758089" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; margin-left: 24px; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;" xml:lang="EN-US">
<b><u><span style="font-size: large;"><a href="https://www.ncbi.nlm.nih.gov/pubmed/30655581#" target="_blank"><span class="TextRun SCXW162450012 BCX0" data-contrast="auto" lang="EN-US" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; line-height: 19.425px; margin: 0px; padding: 0px;" xml:lang="EN-US"><span class="NormalTextRun SCXW162450012 BCX0" data-wac-het="1" style="-webkit-user-drag: none; background-color: inherit; margin: 0px; padding: 0px;"></span></span><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559685":360,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; line-height: 19.425px; margin: 0px; padding: 0px;">Autism and Cannabis - The published Israeli Experience </span></a> </span></u></b><b style="font-family: Calibri, Calibri_EmbeddedFont, Calibri_MSFontService, sans-serif;"><u><span style="font-size: 11pt;">Click For the article </span></u></b></div>
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<div class="Paragraph SCXW162450012 BCX0" lang="EN-US" paraeid="{1918d86a-b026-41ab-a666-89d002ca515b}{91}" paraid="1720588279" style="-webkit-user-drag: none; background-color: transparent; color: windowtext; overflow-wrap: break-word; padding: 0px; vertical-align: baseline;" xml:lang="EN-US">
<span style="font-size: large;"> </span><a href="https://www.ncbi.nlm.nih.gov/sites/myncbi/103bGJGeIgzQv/collections/57793109/public/" target="_blank"><span class="EOP SCXW162450012 BCX0" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}" data-wac-het="1" style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: large; line-height: 19.425px; margin: 0px; padding: 0px;">Autism and Cannabis and Sleep: </span><span style="background-color: transparent; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif;"><span style="font-size: x-small;">Peer- Reviewed Literature Search</span></span></a></div>
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Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-7184381963015173242020-04-16T18:50:00.003-05:002020-04-18T19:52:29.768-05:00Autism and Cannabis CBD THC - Join US for a Morning Discussion<h1 style="box-sizing: border-box; caret-color: rgb(102, 102, 102); color: #666666; font-family: "Helvetica Neue", sans-serif; font-size: 34px; line-height: 1.3em; margin: 0px 0px 16px; padding: 0px; text-align: center; text-transform: capitalize; word-wrap: break-word;">
Curious About Medical Cannabis And Autism?</h1>
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When: Tuesday, April 21st, 2020 at 7:30 AM</h3>
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Space is limited so <a href="https://zoom.us/webinar/register/WN_rPjey6DSRqOxGvC88aAPuQ" rel="noopener noreferrer" style="border: 0px; box-sizing: border-box; color: #1e73be; margin: 0px; outline: none 0px; padding: 0px; text-decoration: none; vertical-align: baseline; word-wrap: break-word;" target="_blank">register TODAY</a>!</h3>
<div style="border: 0px; box-sizing: border-box; caret-color: rgb(102, 102, 102); color: #666666; font-family: "Helvetica Neue", sans-serif; font-size: 18px; line-height: 1.5em; margin-bottom: 20px; padding: 0px; text-align: center; vertical-align: baseline; word-wrap: break-word;">
Join us for an interactive discussion with Dr. Joshua Rotenberg, Pediatric Neurologist. Dr. Rotenberg will be sharing his knowledge and experience as a physician in the Compassionate Use Program treating pediatric patients diagnosed with Autism. </div>
<div style="border: 0px; box-sizing: border-box; caret-color: rgb(102, 102, 102); color: #666666; font-family: "Helvetica Neue", sans-serif; font-size: 18px; line-height: 1.5em; margin-bottom: 20px; padding: 0px; text-align: center; vertical-align: baseline; word-wrap: break-word;">
Dr. Joshua Rotenberg practices at <a href="https://myspecialist.clinic/" rel="noopener noreferrer" style="border: 0px; box-sizing: border-box; color: #1e73be; margin: 0px; outline: none 0px; padding: 0px; text-decoration: none; vertical-align: baseline; word-wrap: break-word;" target="_blank">Houston Specialty Clinic</a>.</div>
<div style="border: 0px; box-sizing: border-box; caret-color: rgb(102, 102, 102); color: #666666; font-family: "Helvetica Neue", sans-serif; font-size: 18px; line-height: 1.5em; margin-bottom: 20px; padding: 0px; text-align: center; vertical-align: baseline; word-wrap: break-word;">
We are accepting questions in advance! To submit a question to be answered during the discussion, please submit <a href="https://forms.gle/puVtFYZZqxvuTxWv9" rel="noopener noreferrer" style="border: 0px; box-sizing: border-box; color: #1e73be; margin: 0px; outline: none 0px; padding: 0px; text-decoration: none; vertical-align: baseline; word-wrap: break-word;" target="_blank">here</a>.</div>
<div style="border: 0px; box-sizing: border-box; caret-color: rgb(102, 102, 102); color: #666666; font-family: "Helvetica Neue", sans-serif; font-size: 18px; line-height: 1.5em; margin-bottom: 20px; padding: 0px; text-align: center; vertical-align: baseline; word-wrap: break-word;">
We look forward to you joining us!</div>
<div style="border: 0px; box-sizing: border-box; caret-color: rgb(102, 102, 102); color: #666666; font-family: "Helvetica Neue", sans-serif; font-size: 18px; line-height: 1.5em; margin-bottom: 20px; padding: 0px; text-align: center; vertical-align: baseline; word-wrap: break-word;">
Compassionate Cultivation proudly supports the entire Autism Community.</div>
<div style="text-align: right;">
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi9n7kETIArg0xvaEShW6RP4nRVR-OeC59RKj5n6Om7eq7lAA5A_Gb6KeepXVC0mfNi11LFEackyheRUTARqaztGFMqEx9nLaGJOnXBrrWZjwY8pvMPeYNxsFY7CNVRon0QjzMz/s1600/43D81363-AD56-46A2-8EAA-A8112AB59846.png" imageanchor="1" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto;"><img border="0" data-original-height="787" data-original-width="941" height="534" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi9n7kETIArg0xvaEShW6RP4nRVR-OeC59RKj5n6Om7eq7lAA5A_Gb6KeepXVC0mfNi11LFEackyheRUTARqaztGFMqEx9nLaGJOnXBrrWZjwY8pvMPeYNxsFY7CNVRon0QjzMz/s640/43D81363-AD56-46A2-8EAA-A8112AB59846.png" width="640" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;"><span style="-webkit-text-size-adjust: auto; background-color: white; caret-color: rgb(26, 42, 42); color: #1a2a2a; font-family: "Josefin Sans"; font-size: 12.67199993133545px;">Online Zoom / FB Live discussions Autism and the Texas Compassionate Use Program</span></td></tr>
</tbody></table>
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Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-16920897893949018072020-04-12T08:09:00.003-05:002020-04-12T11:28:08.571-05:00Is your pediatric neurologist board-certified? <div class="separator" style="clear: both; text-align: left;">
It is important to ask if your physician, in my case, a<a href="https://www.certificationmatters.org/find-my-doctor/"> child neurologist is board-certified</a>.</div>
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<br />Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-51257952130016088052020-03-25T22:25:00.000-05:002020-04-12T09:45:57.581-05:00Pediatric Neurology Telemedicine Tips <i>A NICE GRAPHIC. EXCEPT, WE TRY TO GET PEOPLE USED TO THE PLATFORM WELL-BEFORE VISITS. - JR</i><br />
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<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="float: right; margin-left: 1em; text-align: right;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiEkFA3qRQPYokp0yRUU9uORGUsGnqd3lLQSncmCY-CxZq8ksaBmZ2G1gmOq5SIeMKpm3lGGHj2tGa-rWbhGujbvYVAv-VuUV-j0yNA74oTTtsPEonoQR-kfnAX9Si1eDt3kJzA/s1600/90342590_10216449582016910_8666667455508119552_o.jpg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" data-original-height="1531" data-original-width="800" height="640" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiEkFA3qRQPYokp0yRUU9uORGUsGnqd3lLQSncmCY-CxZq8ksaBmZ2G1gmOq5SIeMKpm3lGGHj2tGa-rWbhGujbvYVAv-VuUV-j0yNA74oTTtsPEonoQR-kfnAX9Si1eDt3kJzA/s640/90342590_10216449582016910_8666667455508119552_o.jpg" width="334" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Pediatric Neurology Telemedicine Tips</td></tr>
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<i><span style="color: red; font-size: large;"><b><a href="https://myspecialist.clinic/">Child & Adolescent Neurology TELEMEDICINE</a></b></span></i><br />
<i><span style="color: red; font-size: large;"><b><a href="https://myspecialist.clinic/houston_coronavirus.html"><br /></a></b></span></i>
<span style="color: red; font-size: large;"><b><i><a href="https://myspecialist.clinic/" target="_blank">Pediatric Pulmonary TELEMEDICINE</a></i></b></span><br />
<span style="color: red; font-size: large;"><b><i><a href="https://myspecialist.clinic/houston_coronavirus.html"><br /></a></i></b></span>
<span style="color: red; font-size: large;"><b><i><a href="https://myspecialist.clinic/" target="_blank">Sleep Disorders Telemedicine</a></i></b></span><br />
<span style="color: red; font-size: large;"><b><i><a href="https://myspecialist.clinic/houston_coronavirus.html"><br /></a></i></b></span><span style="font-size: large;"><b><i><span style="color: red;"><a href="https://myspecialist.clinic/houston_coronavirus.html" target="_blank">Pediatric Neurology Coronavirus Emergency Telemedicine link HERE! </a></span></i></b></span><br />
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Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-69219356494130556812020-03-19T11:54:00.002-05:002020-04-12T09:48:55.024-05:00Pediatric Neurology Services at Home During Corona / Covid -19 <div style="background-color: white; border: 0px; clear: both; font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-size: 12px; font-stretch: inherit; font-variant-east-asian: inherit; font-variant-numeric: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">
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<tr><td style="text-align: center;"><a href="https://www.fijivillage.com/news_images/7063801245e72bfcc22ee6fe7369ac.jpg" imageanchor="1" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto;"><img alt="Image result for covid 19 child" border="0" height="112" src="https://www.fijivillage.com/news_images/7063801245e72bfcc22ee6fe7369ac.jpg" width="200" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Social Distancing Saves Lives in Child Neurology Too</td></tr>
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<span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; color: #0b5394; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">19 March 2020</span></span></div>
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<span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"></span></span><br /></span>
<span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; color: #0b5394; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"></span></span></div>
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<span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; color: #0b5394; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">To: HSC <a href="http://myspecialist.clinic/" target="_blank">Houston Specialty Clinic Child Adolescent Neurology Patients</a></span></span></div>
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<span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Subject:<span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Dr.<span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">R</span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">otenberg</span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">, Kara Schmidt</span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">, Testing and EEG </span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span>-</span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span>Appointments<span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">during Coronavirus Emergency</span></span><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></div>
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<b><span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">The State of<span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Texas<span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">is in the midst of a public health emergency due to coronavirus</span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">.</span><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></b></div>
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<b><span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">It is imperative to “flatten the curve” of<span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">this pandemic by practicing<span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> strict </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">social distancing.</span><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></b></div>
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<b><span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">Our practice is committed to our patients' needs.</span><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></b></div>
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<b><span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">We need<span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">to make changes<span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">to safely deliver care under these unusual circumstances. </span></span></b></div>
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<span lang="en-US" style="border: 0px; color: #0b5394; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><u><b>Telemedicine visits are an established part of our practice. It's business as usual. </b></u></span></div>
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<div style="border: 0px; clear: both; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">
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<b><span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">Therefore, effective immediately:</span><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></b></div>
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<b><span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">All </span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">appointments<span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">will be<span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">moved to telemedicine<span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">status<span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">ONLY</span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">.</span></span><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></b></div>
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<li style="clear: both; font-family: Calibri, Calibri_MSFontService, sans-serif; font-size: 11pt;"><div style="color: windowtext;">
<span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">New patients will be completed by telemedicine</span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"> </span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-weight: bold; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">ONLY</span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">. </span></span></div>
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<span style="border: 0px; color: #0b5394; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><b>Most testing, dietician consults will be completed by telemedicine. </b></span></div>
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<span style="color: #0b5394; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-style: inherit;"><b>There will be very few exceptions based on medical need. </b></span></div>
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<span style="color: #0b5394; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: inherit; font-style: inherit;"><b>EEG visits will be rescheduled to a different time or place. </b></span></div>
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<span style="font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif;"><span style="color: #0b5394; font-size: 14.6667px;"><b><a href="http://myspecialist.clinic/" target="_blank"><u>Regarding pulmonary: </u> Dr. Susarla </a>to release updated guidelines later today. </b></span></span></div>
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<b><span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">This<span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">process<span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></span><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">will stay in place during the course of this emergency. </span></span></b></div>
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<span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><b></b></span><br /></span>
<span lang="en-US" style="border: 0px; color: #0b5394; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><b></b></span></div>
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<span lang="en-US" style="border: 0px; color: #0b5394; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><b>Please call your insurance and/or employer to check telemedicine benefits. </b></span></div>
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<span style="color: #0b5394;"><b><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"></span></b><br /></span>
<b><span style="border: 0px; color: #0b5394; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"></span></b></div>
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<b><span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"></span></span><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">Thank you, </span></span></b></div>
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<span style="color: #0b5394;"><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><b></b></span><br /></span>
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<div style="background-color: white; border: 0px; clear: both; font-family: "Segoe UI", "Segoe UI Web", Arial, Verdana, sans-serif; font-stretch: inherit; font-variant-east-asian: inherit; font-variant-numeric: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">
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<b><span style="color: #0b5394;"><span lang="en-US" style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;">Dr. Rotenberg</span><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"> </span></span></b></div>
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<span style="color: #0b5394;"><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"></span><br /></span>
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<span style="color: #0b5394;"><span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="font-size: large;"></span></span><br /></span>
<span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><span style="color: #0b5394; font-size: large;"></span></span></div>
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<span style="border: 0px; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-stretch: inherit; font-style: inherit; font-variant: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><b><u><span style="color: #0b5394; font-size: large;">Information on Covid19</span></u></b></span></div>
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<span style="border: 0px; color: inherit; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"></span><br />
<span style="border: 0px; color: inherit; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"></span></div>
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<span style="border: 0px; color: inherit; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><a href="https://www.facebook.com/groups/coronavirus.houston/">https://www.facebook.com/groups/coronavirus.houston/</a></span></div>
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<span style="border: 0px; color: inherit; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"></span><br />
<span style="border: 0px; color: inherit; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"></span></div>
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<span style="border: 0px; color: inherit; font-family: "calibri" , "calibri_embeddedfont" , "calibri_msfontservice" , sans-serif; font-size: 11pt; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 19.425px; margin: 0px; padding: 0px; vertical-align: baseline;"><a href="http://publichealth.harriscountytx.gov/Resources/2019-Novel-Coronavirus">http://publichealth.harriscountytx.gov/Resources/2019-Novel-Coronavirus</a></span><br />
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<b><u><span style="font-size: large;">Texas Telemedicine</span></u></b></div>
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Governor Abbott Waives Certain Regulations For Telemedicine Care In Texas</h1>
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March 17, 2020 | Austin, Texas | <a href="https://gov.texas.gov/news/category/press-release" style="background-color: transparent; box-sizing: inherit; cursor: pointer; line-height: inherit;">Press Release</a></div>
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Governor Greg Abbott today waived certain regulations and directed that the Texas Department of Insurance (TDI) issue an emergency rule, all relating to telemedicine care for patients with state-regulated insurance plans to help doctors across Texas continue to treat their patients while mitigating the spread of COVID-19. The suspensions and emergency rule will work together to allow telemedicine visits for patients with state-regulated plans to be paid the same as in-office visits for insurance purposes. These actions build upon waivers the Governor issued last week of portions in the Occupations Code to expand provider flexibility in providing medical services over the phone.</div>
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“As the State of Texas responds to COVID-19, we continue to work to maintain regular health care services and operations throughout the state, and telemedicine is one of the most valuable tools we have to ensure Texans continue to receive the health services they need,” said Governor Abbott. “Expanding telemedicine options will help protect the health of patients and health care professionals, and help Texas mitigate the spread of COVID-19.”</div>
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Doctors will be eligible for payment from insurance plans regulated by TDI for medical visits they conduct over the phone instead of in-person at the same rate they would receive for in-person visits. </div>
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Medical providers seeking guidance on the impact of the new rule can expect guidance from the Texas Medical Board to be issued in the coming days, including administrative guidance for billing to ensure that claims are processed smoothly.</div>
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Insurers seeking guidance on implementation of the emergency rule should contact TDI or visit their <a href="https://www.tdi.texas.gov/" style="background-color: transparent; box-sizing: inherit; color: #022e92; cursor: pointer; line-height: inherit;">webpage</a> for more information.</div>
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This coordinated efforts between the Office of the Governor, the Texas Department of Insurance, the Texas Medical Board, and health insurance plans will increase access to health care for all Texans. Today’s action will expand telemedicine options by giving health care providers greater flexibility to perform audio-only telephone consultations with their patients.</div>
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As a reminder, Texans covered by CHIP or Medicaid will not be charged copays for test or telemedicine consults. Individuals covered by Medicare or large employer plans should check with their health plan administrator to determine their specific benefits. </div>
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Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-89945027495786900252020-03-18T13:37:00.001-05:002020-04-12T09:46:56.311-05:00Epilepsy & Covid-19 Coronavirus <br />
Epilepsy Coronavirus Covid-19 - A great site from the Epilepsy Foundation<br />
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FB meetup on 18 March<br />
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Concerns About COVID-19 (Coronavirus) and Epilepsy</h1>
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CONTENT HIGHLIGHTS</div>
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<li style="box-sizing: border-box;"><span style="color: #3561c6;"><span style="box-sizing: border-box;">Are people with epilepsy at higher risk of developing COVID-19 (coronavirus)?</span></span></li>
<li style="box-sizing: border-box;"><span style="color: #3561c6;"><span style="box-sizing: border-box;">Can COVID-19 increase seizures if a person gets the virus?</span></span></li>
<li style="box-sizing: border-box;"><span style="color: #3561c6;"><span style="box-sizing: border-box;">How can I get more medicine if my health care provider prescribes it?</span></span></li>
<li style="box-sizing: border-box;"><span style="color: #3561c6;"><span style="box-sizing: border-box;">Are there shortages in seizure medicines in the United States?</span></span></li>
<li style="box-sizing: border-box;"><span style="color: #3561c6;"><span style="box-sizing: border-box;">If COVID-19 is in my community, what should I do?</span></span></li>
<li style="box-sizing: border-box;"><span style="color: #3561c6;"><span style="box-sizing: border-box;">How do I protect myself from getting sick?</span></span></li>
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<a href="https://www.epilepsy.com/article/2020/3/concerns-about-covid-19-coronavirus-and-epilepsy" target="_blank">COVID-19 Epilepsy Information More Here</a></div>
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Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-38932528252813149422020-03-04T17:08:00.004-06:002020-03-04T17:09:17.250-06:00Magnesium, tics, Tourette syndrome Magnesium Tourette Syndrome and Tics<br />
<br />
I often have questions about magnesium for tics and Tourette’s syndrome.<br />
<br />
One open label study showed benefit using IV magnesium with B6. It appears that a double blind placebo controlled trial was planned but results have not been published.<br />
<br />
One must keep in mind that the potential side-effects of high doses of magnesium are probably unsafe and that magnesium itself can have side effects.<br />
<br />
So, is the Research promising? Yes.<br />
Do I recommend IV magnesium for tics? Normally, no. There are too many risks.<br />
Screen for magnesium or zinc deficiency in at-risk children? I think so.<br />
<br />
<a href="https://www.ncbi.nlm.nih.gov/sites/myncbi/103bGJGeIgzQv/collections/59375779/public/" target="_blank">Articles on pubmed are here</a><br />
<br />
<a href="https://www.webmd.com/vitamins/ai/ingredientmono-998/magnesium">https://www.webmd.com/vitamins/ai/ingredientmono-998/magnesium</a>I often have questions about magnesium for ticks and Tourette’s syndrome.Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-13510207932312587782020-02-29T10:41:00.003-06:002020-02-29T10:41:37.063-06:00Brain Injury Recovery with Transcranial Electrical Therapy <b><u>TDCS for Brain Injury</u></b><br />
<br />
I have reviewed data and it tends to fall in favor of efficacy.<br />
<br />
If symptoms persist, this modality should be considered.<br />
<br />
<a href="https://www.ncbi.nlm.nih.gov/sites/myncbi/103bGJGeIgzQv/collections/58666066/public/">https://www.ncbi.nlm.nih.gov/sites/myncbi/103bGJGeIgzQv/collections/58666066/public/</a><br />
<br />
<br />Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-36047493226692185522020-02-10T17:14:00.001-06:002020-02-10T17:14:09.871-06:00A book for Siblings of Kids with Special Needs - "I am Special Too" <div class="separator" style="clear: both; text-align: center;">
<a href="https://encrypted-tbn3.gstatic.com/images?q=tbn:ANd9GcSYnjkCJOA5ce-aWIr83tk74nHnG8wQuw49t3dSaHH6EGvtYJT9" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><img alt="Image result for i am special too noah rubinson" border="0" height="246" src="https://encrypted-tbn3.gstatic.com/images?q=tbn:ANd9GcSYnjkCJOA5ce-aWIr83tk74nHnG8wQuw49t3dSaHH6EGvtYJT9" style="color: #222222; font-family: arial, sans-serif; font-size: 14px;" width="320" /></a></div>
I just got my copies. Wow!<br />
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<div class="NFQFxe Hhmu2e viOShc LKPcQc mod" data-hveid="CBEQAQ" data-md="16" data-ved="2ahUKEwiz653njMjnAhUJWK0KHa13DqAQhygoADAUegQIERAB" lang="en-US" style="border-radius: 8px; border-top: 0px; clear: none; line-height: 1.57; overflow: inherit; padding-top: 0px;">
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<div class="separator" style="clear: both; text-align: center;">
<a href="https://encrypted-tbn3.gstatic.com/images?q=tbn:ANd9GcSYnjkCJOA5ce-aWIr83tk74nHnG8wQuw49t3dSaHH6EGvtYJT9" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><span style="color: rgba(0, 0, 0, 0.87); font-family: arial, sans-serif-light, sans-serif; font-size: 30px; text-align: center;">I Am Special Too</span></a><a href="https://encrypted-tbn3.gstatic.com/images?q=tbn:ANd9GcSYnjkCJOA5ce-aWIr83tk74nHnG8wQuw49t3dSaHH6EGvtYJT9" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"><span style="color: #70757a; text-align: start;">Book by Noah Alexander Rubinson</span></a></div>
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<div style="color: #333333; font-family: Arial, sans-serif; font-size: 13px; margin-bottom: 1.3em; padding: 0px;">
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<div style="color: #333333; font-family: Arial, sans-serif; font-size: 13px; margin-bottom: 1.3em; padding: 0px;">
Picture the life of a child with special needs. What do you see? Frequent trips to the doctor? Simple everyday activities made significantly more difficult by irreversible developmental delays? A young boy or girl struggling to navigate the world, weighed down by a disability over which they have no control?</div>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://encrypted-tbn3.gstatic.com/images?q=tbn:ANd9GcSYnjkCJOA5ce-aWIr83tk74nHnG8wQuw49t3dSaHH6EGvtYJT9" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"></a></div>
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Now visualize the daily struggles of that child's family members. Is the child's mother or father forced to leave the workforce to raise their son or daughter? </div>
<div style="color: #333333; font-family: Arial, sans-serif; font-size: 13px; margin-bottom: 1.3em; padding: 0px;">
<a href="https://g.co/kgs/VE9Z26" target="_blank">More Here</a></div>
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Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-91195507600601125182020-02-10T16:47:00.000-06:002020-02-10T16:47:19.783-06:00Dr Josh Rotenberg Houston Top Child Neurologist - 6 Years in a Row<i>Gratified to be chosen as a Top Doctor for the Houston Texas Region. </i><table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjybfjwpjflpliJP0Kn1WDayirLiG_WGznY9ate7CDC39rSSJOnIbYw3xUavoDk4-Aq6brHKIt9UK14BzeqHnXM7Wo9rvJb9UH2NbQiU7K7iRQePa1T0raoT2E5yfEMdd5J8EGO/s1600/5+years+of+top+doctors.JPG" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" data-original-height="357" data-original-width="1600" height="142" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjybfjwpjflpliJP0Kn1WDayirLiG_WGznY9ate7CDC39rSSJOnIbYw3xUavoDk4-Aq6brHKIt9UK14BzeqHnXM7Wo9rvJb9UH2NbQiU7K7iRQePa1T0raoT2E5yfEMdd5J8EGO/s640/5+years+of+top+doctors.JPG" width="640" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Dr. Rotenberg selected by peers for top pediatric neurology in Houston Texas<br /></td></tr>
</tbody></table>
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><img border="0" data-original-height="700" data-original-width="477" height="400" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg0h3GKnxWXShZBxrFAnuEIqpELaV0xvXFBAmjC2nrVLBYfR9ydxma5Rapz1fkavrVAL48roZrHpktUtrw-rpQMQfAxkVsMLq4ZOoAdholU-OkkvGxmDnznhNTlp-xGq9ioBf-U/s400/castle+connoly+2020.JPG" style="margin-left: auto; margin-right: auto;" width="271" /></td></tr>
<tr><td class="tr-caption" style="text-align: center;">2020 Top Pediatric Neurology Houston TX</td></tr>
</tbody></table>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg0h3GKnxWXShZBxrFAnuEIqpELaV0xvXFBAmjC2nrVLBYfR9ydxma5Rapz1fkavrVAL48roZrHpktUtrw-rpQMQfAxkVsMLq4ZOoAdholU-OkkvGxmDnznhNTlp-xGq9ioBf-U/s1600/castle+connoly+2020.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"></a><br /><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg0h3GKnxWXShZBxrFAnuEIqpELaV0xvXFBAmjC2nrVLBYfR9ydxma5Rapz1fkavrVAL48roZrHpktUtrw-rpQMQfAxkVsMLq4ZOoAdholU-OkkvGxmDnznhNTlp-xGq9ioBf-U/s1600/castle+connoly+2020.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"></a></div>
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<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgIsPoa6EUm_rk5lnC7o3PYGrxZo8LBLFJ77H6fN6RhZhmY3-7pI5v76WgAeibDvuqJJNX-yGpaKmFKLZgDBYuNRl3kmMXkmFZnw7Msh71ms0Lg_vcNEF9j1uYXqm3RsZaPnwU3/s1600/top+doc+2018.JPG" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" data-original-height="1148" data-original-width="793" height="400" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgIsPoa6EUm_rk5lnC7o3PYGrxZo8LBLFJ77H6fN6RhZhmY3-7pI5v76WgAeibDvuqJJNX-yGpaKmFKLZgDBYuNRl3kmMXkmFZnw7Msh71ms0Lg_vcNEF9j1uYXqm3RsZaPnwU3/s400/top+doc+2018.JPG" width="276" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">2018 Top Child Neurology - Houston</td></tr>
</tbody></table>
<br />
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhA3BRzJo2TtFdL9b0BWA4fke_tbMFy8LQCpEowGga85DGYTziIC5jq_XiifcZ-hXElXaeqztWsa-Orjz93agtou89IFZPOHL2BSUAmyJYVIHPalsUsk6Kboiy_5p_5X21hXE3-/s1600/top+docs+2019.JPG" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" data-original-height="1162" data-original-width="803" height="400" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhA3BRzJo2TtFdL9b0BWA4fke_tbMFy8LQCpEowGga85DGYTziIC5jq_XiifcZ-hXElXaeqztWsa-Orjz93agtou89IFZPOHL2BSUAmyJYVIHPalsUsk6Kboiy_5p_5X21hXE3-/s400/top+docs+2019.JPG" width="276" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">2019 Top Child Neurologist - Houston Texas</td></tr>
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<br />Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-54262393165071066872020-02-04T21:51:00.000-06:002020-02-10T17:06:27.114-06:00Autism, Cognitive Impairment Genetics - ZNF292 Variants in NeuroDevelopmental Disorders<i>This disorder has incomplete penetrance and a </i><br />
<table cellpadding="0" cellspacing="0" class="tr-caption-container" style="float: right; margin-left: 1em; text-align: right;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEheHwO-gMrIA0FYNPiv_XmZskQ7ojdcqjpi7Ni-CdGnJP3dGfWqFJguXHKoqHtWSHX3xZulyR7RxVgHgyL67iy0uMQU_CqpN_D-UBt-FW09g3txiQ090QkMAe66h_A2nmoCuutF/s1600/0DABBB1F-DC4F-4941-B3BE-36C60611A076.png" imageanchor="1" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto;"><i><img border="0" data-original-height="345" data-original-width="685" height="161" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEheHwO-gMrIA0FYNPiv_XmZskQ7ojdcqjpi7Ni-CdGnJP3dGfWqFJguXHKoqHtWSHX3xZulyR7RxVgHgyL67iy0uMQU_CqpN_D-UBt-FW09g3txiQ090QkMAe66h_A2nmoCuutF/s320/0DABBB1F-DC4F-4941-B3BE-36C60611A076.png" width="320" /></i></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;"><i>MRI findings </i></td></tr>
</tbody></table>
<br />
<table cellpadding="0" cellspacing="0" class="tr-caption-container" style="float: right; margin-left: 1em; text-align: right;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEietQxGTJHNQz3OyGig1EtEnl2Ksh1TPKc9-7D_Uy5k0ctdz9MaPDf6YWkTwfDL2wOQFgKg9DXGln9V_wOYibpQzombhTdTUalmiNEMMxMY0PTArKZqZKIDL1B6ZaYCyHDxHTWo/s1600/6B3EDA32-3748-4EBA-932B-803942115CA3.png" imageanchor="1" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto;"><i><img border="0" data-original-height="342" data-original-width="685" height="158" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEietQxGTJHNQz3OyGig1EtEnl2Ksh1TPKc9-7D_Uy5k0ctdz9MaPDf6YWkTwfDL2wOQFgKg9DXGln9V_wOYibpQzombhTdTUalmiNEMMxMY0PTArKZqZKIDL1B6ZaYCyHDxHTWo/s320/6B3EDA32-3748-4EBA-932B-803942115CA3.png" width="320" /></i></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;"><i>Features of ZNF292 neurodevelopmental disorder</i></td></tr>
</tbody></table>
<i>very broad spectrum of presentation from ADD/ADHD to autism and cognitive impairment. The gene can be medically relevant. - JR</i><br />
<i><br /></i>
<i>P.s. Thankful that I could contribute</i><br />
<br />
<br />
<h1 class="heading-title" style="-webkit-text-size-adjust: 100%; box-sizing: inherit; caret-color: rgb(33, 33, 33); clear: both; color: #212121; font-family: Merriweather, Georgia, Cambria, "Times New Roman", Times, serif; font-size: 2.6rem; line-height: 1.4; margin: 0px 0px 1.6rem; word-wrap: break-word;">
De Novo and Inherited Variants in ZNF292 Underlie a Neurodevelopmental Disorder With Features of Autism Spectrum Disorder</h1>
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<h2 class="title" style="-webkit-text-size-adjust: 100%; box-sizing: inherit; caret-color: rgb(33, 33, 33); clear: both; color: #212121; font-family: Merriweather, Georgia, Cambria, "Times New Roman", Times, serif; font-size: 2rem; line-height: 2.4rem; margin-bottom: 1.2rem; margin-top: 3.6rem;">
<a href="https://www.ncbi.nlm.nih.gov/pubmed/31723249https://www.ncbi.nlm.nih.gov/pubmed/31723249" target="_blank">Article here</a></h2>
<h2 class="title" style="-webkit-text-size-adjust: 100%; box-sizing: inherit; caret-color: rgb(33, 33, 33); clear: both; color: #212121; font-family: Merriweather, Georgia, Cambria, "Times New Roman", Times, serif; font-size: 2rem; line-height: 2.4rem; margin-bottom: 1.2rem; margin-top: 3.6rem;">
Abstract</h2>
<div class="abstract-content selected" id="en-abstract" style="-webkit-text-size-adjust: 100%; box-sizing: inherit; caret-color: rgb(33, 33, 33); clear: left; color: #212121; font-family: BlinkMacSystemFont, -apple-system, "Segoe UI", Roboto, Oxygen, Ubuntu, Cantarell, "Fira Sans", "Droid Sans", "Helvetica Neue", sans-serif; font-size: 16px;">
<div style="box-sizing: inherit; line-height: 1.5; margin-bottom: 1.2rem; margin-top: 1.2rem;">
<strong class="sub-title" style="box-sizing: inherit;">Purpose: </strong>Intellectual disability (ID) and autism spectrum disorder (ASD) are genetically heterogeneous neurodevelopmental disorders. We sought to delineate the clinical, molecular, and neuroimaging spectrum of a novel neurodevelopmental disorder caused by variants in the zinc finger protein 292 gene (ZNF292).</div>
<div style="box-sizing: inherit; line-height: 1.5; margin-bottom: 1.2rem; margin-top: 1.2rem;">
<strong class="sub-title" style="box-sizing: inherit;">Methods: </strong>We ascertained a cohort of 28 families with ID due to putatively pathogenic ZNF292 variants that were identified via targeted and exome sequencing. Available data were analyzed to characterize the canonical phenotype and examine genotype-phenotype relationships.</div>
<div style="box-sizing: inherit; line-height: 1.5; margin-bottom: 1.2rem; margin-top: 1.2rem;">
<strong class="sub-title" style="box-sizing: inherit;">Results: </strong>Probands presented with ID as well as a spectrum of neurodevelopmental features including ASD, among others. All ZNF292 variants were de novo, except in one family with dominant inheritance. ZNF292 encodes a highly conserved zinc finger protein that acts as a transcription factor and is highly expressed in the developing human brain supporting its critical role in neurodevelopment.</div>
<div style="box-sizing: inherit; line-height: 1.5; margin-bottom: 1.2rem; margin-top: 1.2rem;">
<strong class="sub-title" style="box-sizing: inherit;">Conclusion: </strong>De novo and dominantly inherited variants in ZNF292 are associated with a range of neurodevelopmental features including ID and ASD. The clinical spectrum is broad, and most individuals present with mild to moderate ID with or without other syndromic features. Our results suggest that variants in ZNF292 are likely a recurrent cause of a neurodevelopmental disorder manifesting as ID with or without ASD.</div>
</div>
<div style="-webkit-text-size-adjust: 100%; box-sizing: inherit; caret-color: rgb(33, 33, 33); color: #212121; font-family: BlinkMacSystemFont, -apple-system, "Segoe UI", Roboto, Oxygen, Ubuntu, Cantarell, "Fira Sans", "Droid Sans", "Helvetica Neue", sans-serif; font-size: 16px; line-height: 1.5; margin-bottom: 1.2rem; margin-top: 1.2rem;">
<strong class="sub-title" style="box-sizing: inherit;">Keywords: </strong>ZNF292; autism spectrum disorders; exome sequencing; intellectual disability; next-generation sequencing.</div>
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<i style="-webkit-text-size-adjust: 100%; caret-color: rgb(34, 34, 34); color: #222222; font-family: Lora, Palatino, Times, "Times New Roman", serif; font-size: 18px;">“ZNF292</i><span style="background-color: white; color: #222222; font-family: "lora" , "palatino" , "times" , "times new roman" , serif; font-size: 18px;"> encodes a highly conserved zinc finger protein that acts as a transcription factor. </span><i style="-webkit-text-size-adjust: 100%; caret-color: rgb(34, 34, 34); color: #222222; font-family: Lora, Palatino, Times, "Times New Roman", serif; font-size: 18px;">ZNF292</i><span style="background-color: white; color: #222222; font-family: "lora" , "palatino" , "times" , "times new roman" , serif; font-size: 18px;"> is composed of eight exons, the last of which is the largest and encodes all 16 highly conserved zinc fingers of the predicted 2723-residue protein (canonical transcript in GenBank: NM_015021.2). Three of these zinc fingers (10–12) bind DNA at the promoter of growth hormone where it cooperates with POU1F1, a member of the POU family of transcription factors known to activate transcription in somatotrophs.</span><span style="color: #222222; font-family: "lora" , "palatino" , "times" , "times new roman" , serif; font-size: 13.5px; line-height: 0; position: relative; top: -0.5em; vertical-align: baseline;"><a aria-label="Reference 5" data-test="citation-ref" data-track-action="reference anchor" data-track-label="link" data-track="click" href="https://www.nature.com/articles/s41436-019-0693-9#ref-CR5" id="ref-link-section-d37404e2556" style="color: #006699; text-decoration-skip: objects; text-decoration: none; vertical-align: baseline; word-break: break-word; word-wrap: break-word;" title="Lipkin SM, Naar AM, Kalla KA, Sack RA, Rosenfeld MG. Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression. Genes Dev. 1993;7:1674–1687.">5</a></span><span style="background-color: white; color: #222222; font-family: "lora" , "palatino" , "times" , "times new roman" , serif; font-size: 18px;"> Accordingly, the ZNF292 protein was originally described as an enhancer of growth hormone (GH) expression in the pituitary gland of a rat animal model.</span><span style="color: #222222; font-family: "lora" , "palatino" , "times" , "times new roman" , serif; font-size: 13.5px; line-height: 0; position: relative; top: -0.5em; vertical-align: baseline;"><a aria-label="Reference 5" data-test="citation-ref" data-track-action="reference anchor" data-track-label="link" data-track="click" href="https://www.nature.com/articles/s41436-019-0693-9#ref-CR5" id="ref-link-section-d37404e2560" style="color: #006699; text-decoration-skip: objects; text-decoration: none; vertical-align: baseline; word-break: break-word; word-wrap: break-word;" title="Lipkin SM, Naar AM, Kalla KA, Sack RA, Rosenfeld MG. Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression. Genes Dev. 1993;7:1674–1687.">5</a></span><span style="background-color: white; color: #222222; font-family: "lora" , "palatino" , "times" , "times new roman" , serif; font-size: 18px;"> Its role was further delineated as a tumor suppressor with critical roles in tumor development and progression.</span><span style="color: #222222; font-family: "lora" , "palatino" , "times" , "times new roman" , serif; font-size: 13.5px; line-height: 0; position: relative; top: -0.5em; vertical-align: baseline;"><a aria-label="Reference 6" data-test="citation-ref" data-track-action="reference anchor" data-track-label="link" data-track="click" href="https://www.nature.com/articles/s41436-019-0693-9#ref-CR6" id="ref-link-section-d37404e2564" style="color: #006699; text-decoration-skip: objects; text-decoration: none; vertical-align: baseline; word-break: break-word; word-wrap: break-word;" title="Takeda H, Wei Z, Koso H, et al. Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression. Nat Genet. 2015;47:142–150.">6</a></span><span style="background-color: white; color: #222222; font-family: "lora" , "palatino" , "times" , "times new roman" , serif; font-size: 18px;"> However, the role of </span><i style="-webkit-text-size-adjust: 100%; caret-color: rgb(34, 34, 34); color: #222222; font-family: Lora, Palatino, Times, "Times New Roman", serif; font-size: 18px;">ZNF292</i><span style="background-color: white; color: #222222; font-family: "lora" , "palatino" , "times" , "times new roman" , serif; font-size: 18px;"> in neurodevelopment is virtually unknown.”</span></div>
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Ghayda M. Mirzaa, MD 1,2,3, Jessica X. Chong, PhD2,3, Amélie Piton, MD4,5, Bernt Popp, MD6, Kimberly Foss, MS1, Hui Guo, PhD7, Ricardo Harripaul, MSc8,9, Kun Xia, PhD7, Joshua Scheck, BS1, Kimberly A. Aldinger, PhD1, Samin A. Sajan, PhD10, Sha Tang, PhD11, Dominique Bonneau, MD, PhD12,13, Anita Beck, MD, PhD2, Janson White, PhD14, Sonal Mahida, MGC, CGC15, Jacqueline Harris, MD15, Constance Smith-Hicks, MD, PhD15, Juliane Hoyer, MD6, Christiane Zweier, MD, PhD6, André Reis, MD6, Christian T. Thiel, MD6, Rami Abou Jamra, MD16, Natasha Zeid, MS, CGC17, Amy Yang, MD18,</div>
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Laura S. Farach, MD19, Laurence Walsh, MD20, Katelyn Payne, MS, CGC20, Luis Rohena, MD21,22,</div>
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Milen Velinov, MD, PhD23, Alban Ziegler, MD12,24, Elise Schaefer, MD, PhD25,</div>
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Vincent Gatinois, MD, PhD26,27,28, David Geneviève, MD, PhD26,27,28, Marleen E. H. Simon, MD29, Jennefer Kohler, MS30, Joshua Rotenberg, MD31, Patricia Wheeler, MD32, Austin Larson, MD33, Michelle E. Ernst, MS, CGC34, Cigdem I. Akman, MD34,35, Rachel Westman, MS, CGC36,</div>
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Patricia Blanchet, MD27, Lori-Anne Schillaci, MD37, Catherine Vincent-Delorme, MD38,</div>
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Karen W. Gripp, MD39, Francesca Mattioli, PhD40, Gwenaël Le Guyader, MD, PhD41,</div>
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Bénédicte Gerard, MD4, Michèle Mathieu-Dramard, MD42, Gilles Morin, MD43, Roksana Sasanfar, MD43, Muhammad Ayub, MD44, Nasim Vasli, PhD45, Sandra Yang, MS, CGC46, Rick Person, PhD46,</div>
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Kristin G. Monaghan, PhD46, Deborah A. Nickerson, PhD14, Ellen van Binsbergen, M Gregory M. Enns, MBChB30,47, Annika M. Dries, BS30, Leah J. Rowe, MS, CGC33, Anne C. H. Tsai, MD33, Shayna Svihovec, MS, CGC33, Jennifer Friedman, MD48,49, Zehra Agha, MD50, Raheel Qamar, MD50, Lance H. Rodan, MD51,52, Julian Martinez-Agosto, MD, PhD53, Charlotte W. Ockeloen, MD54,</div>
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Marie Vincent, MD55, William James Sunderland, PhD56, Jonathan A. Bernstein, MD, PhD30,47, Undiagnosed Diseases Network, Evan E. Eichler, PhD14,58, John B. Vincent, PhD8,9,</div>
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University of Washington Center for Mendelian Genomics (UW-CMG), Michael J. Bamshad, MD2,3</div>
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1Center for Integrative Brain Research, Seattle Children’s Research Institute, Seattle, WA, USA; 2Division of Genetic Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA; 3Brotman Baty Institute for Precision Medicine, Seattle, Washington, USA; 4Molecular Genetic Unit, Strasbourg University Hospital, Strasbourg, France; 5Institute of Genetics and Molecular and Cellular Biology, Université de Strasbourg, Illkirch, France; 6Institute of Human Genetics, University Hospital Elrangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany; 7Center for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China; 8The Campbell Family Mental Health Research Institute, Centre for Addiction & Mental Health (CAMH), Toronto, ON, Canada; 9Institute of Medical Science, University of Toronto, Toronto, ON, Canada; 10Department of Clinical Genomics, Ambry Genetics, Aliso Viejo, CA, USA; 11WuXi NextCODE, Cambridge, MA, USA; 12Département de Biochimie et de Génétique, CHU d’Angers, Angers, France; 13UMR INSERM 1083 CNRS 6015, Angers, France; 14Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA; 15Department of Neurogenetics, Kennedy Krieger Institute, Baltimore, MD, USA; 16Institute of Human Genetics, University Medical Center Leipzig, Leipzig, Germany; 17Yale New Haven Health, New Haven, CT, USA; 18Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR, USA; 19Department of Pediatrics, McGovern Medical School at the University of Texas Health Sciences Center, Houston, TX, USA; 20Indiana University Health at Riley Hospital for Children, Indianapolis, IN, USA; 21Division of Genetics, Department of Pediatrics, San Antonio Military Medical Center, San Antonio, TX, USA; 22Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; 23New York State Institute for Basic Research in Developmental Disability, NY, Staten Island, USA; 24Service de Génétique Médicale, Centre hospitalier, Le Mans, France; 25Service de Génétique Médicale, Hôpitaux Universitaires de Strasbourg, Institut de Génétique Médicale d’Alsace, Strasbourg, France; 26Service de génétique clinique, Département de Génétique Médicale, Maladies Rares et Médecine Personnalisée, Strasbourg, France; 27Centre de Référence Maladies Rares Anomalies du Développement et Syndromes Malformatifs Sud-Ouest Occitanie Réunion, Hôpital Arnaud de Villeneuve, Montpellier, France; 28Université Montpellier, Unité Inserm U1183, Montpellier, France; 29Department of Genetics, University Medical Center Utrecht, Utrecht, The Netherlands; 30Stanford Center for Undiagnosed Diseases, Stanford University, Stanford, CA, USA; 31Memorial Hermann Memorial City Medical Center, Houston, TX, USA; Arnold Palmer Hospital for Children, Orlando, FL, USA; 33Section of Genetics, Department of Pediatrics, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, CO, USA; 34Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA; 35Division of Pediatric Neurology, Columbia University Irving Medical Center, New York, NY, USA; 36Division of Genetics, St. Luke’s Clinic, Boise, ID, USA; 37Department of Genetics and Genome Sciences, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; 38Service de Génétique Clinique Guy Fontaine Centre de référence maladies rares Anomalies du dévelopement, Hôpital Jeanne de Flandre Lille, Lille, France; 39Department of Pediatrics, AI duPont Hospital, DE, Wilmington, USA; 40Institut de Genetique et de Biologie Moleculaire et Cellulaire, Illkirch-Graffenstaden, Lille, France; 41Service de Génétique Clinique, Centre de compétence Maladies rares Anomalies du dévelopement, CHU de Poitiers, Poitiers, France; 42Service de Génétique Clinique Centre de référence maladies rares Anomalies du dévelopement, CHU Amiens-Picardie, Amiens, France; 43Children’s Medical Center, UMass Memorial Medical Center, Worcester, MA, USA; 44Department of Psychiatry, Queen’s University, Kingston, ON, Canada; 45Division of Clinical & Metabolic Genetics, Hospital for Sick Children, Toronto, ON, Canada; 46GeneDx, Gaithersburg, MD, USA; Division of Medical Genetics, Department of Pediatrics, Lucile Packard Children’s Hospital, Stanford University, Stanford, CA, USA; 48Departments of Neurosciences and Pediatrics, University of California San Diego and Division of Neurology, Rady Children’s Hospital, San Diego, CA, USA; Rady Children’s Institute for Genomic Medicine, San Diego, CA, USA; 50Department of Biosciences, COMSATS University, Islamabad, Pakistan; 51Division of Genetics and Genomics, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA; 52Department of Neurology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA; 53David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 54Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands; 55CHU de Nantes, Service de génétique médicale, Nantes, France; 56University of Washington Foundation Board, University of Washington, Seattle, WA, USA; 57NIH Undiagnosed Diseases Network, Office of the Director and the National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA; 58Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA.</div>
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Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-20116943248500734042020-02-02T19:33:00.000-06:002020-02-02T19:52:13.260-06:00Concussion in HS football - 1/14 per team in every practice or game?Here is my math.:<br />
<br />
If the risk of brain injury is one in 1000 per athletic exposure in high school football, and<br />
<br />
there are approximately 70 players per team,<br />
<br />
<b><u>then the risk is about 1 in 14 per team per practice or game</u></b>.<br />
<br />
<u><b>So, every 14 games or practices, one student will suffer a brain injury.</b></u><br />
<br />
Girls soccer and boys ice hockey are not much better. But look at the, incidence of concussions in hockey GAMES vs practice.<br />
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<tr><td class="tr-caption" style="text-align: center;">Concussion in high school sports<br /></td></tr>
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<h1 class="highwire-cite-title" id="page-title" style="-webkit-font-smoothing: antialiased; -webkit-text-size-adjust: auto; border: 0px; color: #131313; font-family: "Open Sans", HelveticaNeue, "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 1.8rem; font-stretch: normal; font-weight: normal; letter-spacing: -0.03em; line-height: 1.22em; margin: 0px 0px 20px; outline: 0px; padding: 0px; vertical-align: baseline;">
Concussion Incidence and Trends in 20 High School Sports</h1>
<div class="highwire-cite-authors" style="-webkit-font-smoothing: antialiased; -webkit-text-size-adjust: auto; border: 0px; font-family: "Open Sans", HelveticaNeue, "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 14px; font-stretch: inherit; line-height: 1.33em; margin: 5px 0px 0px; outline: 0px; padding: 0px; vertical-align: baseline;">
<span class="highwire-citation-authors" style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;"><span class="highwire-citation-author first" data-delta="0" style="border-bottom-color: transparent; border-bottom-style: dotted; border-width: 0px 0px 1px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; white-space: nowrap;">Zachary Y. Kerr</span>, <span class="highwire-citation-author" data-delta="1" style="border-bottom-color: transparent; border-bottom-style: dotted; border-width: 0px 0px 1px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; white-space: nowrap;">Avinash Chandran</span>, <span class="highwire-citation-author" data-delta="2" style="border-bottom-color: transparent; border-bottom-style: dotted; border-width: 0px 0px 1px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; white-space: nowrap;">Aliza K. Nedimyer</span>, <span class="highwire-citation-author" data-delta="3" style="border-bottom-color: transparent; border-bottom-style: dotted; border-width: 0px 0px 1px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; white-space: nowrap;">Alan Arakkal</span>, <span class="highwire-citation-author" data-delta="4" style="border-bottom-color: transparent; border-bottom-style: dotted; border-width: 0px 0px 1px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; white-space: nowrap;">Lauren A. Pierpoint</span> and <span class="highwire-citation-author" data-delta="5" style="border-bottom-color: transparent; border-bottom-style: dotted; border-width: 0px 0px 1px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; white-space: nowrap;">Scott L. Zuckerman</span></span></div>
<div class="highwire-cite-metadata" style="-webkit-font-smoothing: antialiased; -webkit-text-size-adjust: auto; border: 0px; font-family: "Open Sans", HelveticaNeue, "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 0.86em; font-stretch: inherit; line-height: 1.33em; margin: 5px 0px 10px; outline: 0px; padding: 0px; vertical-align: baseline;">
<span class="highwire-cite-metadata-journal highwire-cite-metadata" style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">Pediatrics </span><span class="highwire-cite-metadata-date highwire-cite-metadata" style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">November 2019, </span><span class="highwire-cite-metadata-volume highwire-cite-metadata" style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">144 </span><span class="highwire-cite-metadata-issue highwire-cite-metadata" style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">(5) </span><span class="highwire-cite-metadata-pages highwire-cite-metadata" style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">e20192180; </span><span class="highwire-cite-metadata-doi highwire-cite-metadata" style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">DOI: https://doi.org/10.1542/peds.2019-2180</span></div>
<div class="section abstract" id="abstract-2" style="-webkit-font-smoothing: antialiased; -webkit-text-size-adjust: auto; border: 0px; clear: both; font-family: "Open Sans", HelveticaNeue, "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 14px; font-stretch: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">
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Abstract</h2>
<div class="subsection" id="sec-1" style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">
<div id="p-2" style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin-bottom: 15px; outline: 0px; padding: 0px; vertical-align: baseline; word-wrap: break-word;">
<strong style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">BACKGROUND:</strong> Ongoing monitoring of concussion rates and distributions is important in assessing temporal patterns. Examinations of high school sport-related concussions need to be updated. This study describes the epidemiology of concussions in 20 high school sports during the 2013–2014 to 2017–2018 school years.</div>
</div>
<div class="subsection" id="sec-2" style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">
<div id="p-3" style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin-bottom: 15px; outline: 0px; padding: 0px; vertical-align: baseline; word-wrap: break-word;">
<strong style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">METHODS:</strong> In this descriptive epidemiology study, a convenience sample of high school athletic trainers provided injury and athlete exposure (AE) data to the National High School Sports-Related Injury Surveillance Study (High School Reporting Information Online). Concussion rates per 10 000 AEs with 95% confidence intervals (CIs) and distributions were calculated. Injury rate ratios and injury proportion ratios examined sex differences in sex-comparable sports (soccer, basketball, baseball and softball, cross country, track, and swimming). We also assessed temporal trends across the study period.</div>
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<div class="subsection" id="sec-3" style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">
<div id="p-4" style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin-bottom: 15px; outline: 0px; padding: 0px; vertical-align: baseline; word-wrap: break-word;">
<strong style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">RESULTS:</strong> Overall, 9542 concussions were reported for an overall rate of 4.17 per 10 000 AEs (95% CI: 4.09 to 4.26). Football had the highest concussion rate (10.40 per 10 000 AEs). Across the study period, football competition-related concussion rates increased (33.19 to 39.07 per 10 000 AEs); practice-related concussion rates decreased (5.47 to 4.44 per 10 000 AEs). In all sports, recurrent concussion rates decreased (0.47 to 0.28 per 10 000 AEs). Among sex-comparable sports, concussion rates were higher in girls than in boys (3.35 vs 1.51 per 10 000 AEs; injury rate ratio = 2.22; 95% CI: 2.07 to 2.39). Also, among sex-comparable sports, girls had larger proportions of concussions that were recurrent than boys did (9.3% vs 6.4%; injury proportion ratio = 1.44; 95% CI: 1.11 to 1.88).</div>
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<div class="subsection" id="sec-4" style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">
<div id="p-5" style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin-bottom: 15px; outline: 0px; padding: 0px; vertical-align: baseline; word-wrap: break-word;">
<strong style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">CONCLUSIONS:</strong> Rates of football practice-related concussions and recurrent concussions across all sports decreased. Changes in concussion rates may be associated with changes in concussion incidence, diagnosis, and management. Future research should continue to monitor trends and examine the effect of prevention strategies.</div>
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</div>
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<li class="accepted" hwp:start="2019-08-07" style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: 1.5em; margin: 0px 0px 8px; outline: 0px; padding: 0px; vertical-align: baseline;" xmlns:hwp="http://schema.highwire.org/Journal"><span class="accepted-label" style="border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline;">Accepted </span>August 7, 2019.</li>
</ul>
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<li class="fn" id="copyright-statement-1" style="-webkit-font-smoothing: antialiased; border: 0px; font-family: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant-caps: inherit; line-height: 1.5em; margin: 0px 0px 8px; outline: 0px; padding: 0px; vertical-align: baseline;">Copyright © 2019 by the American Academy of Pediatrics</li>
</ul>
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<a href="https://pediatrics.aappublications.org/content/144/5/e20192180">https://pediatrics.aappublications.org/content/144/5/e20192180</a>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-46582778529874788442020-01-26T08:39:00.002-06:002020-01-26T11:21:55.680-06:00Ricky Gervais - Its a Sneezing Tic<i><br /></i>
<i>Dear 60 Minutes Australia, Mr. Woolley and Mr. Gervais, </i><br />
<i><br /></i>
<i>Its an instructive video for people suffering, and though unintended, please don't needlessly add to stigma. #Tourette syndrome is not funny!</i><br />
<i><br /></i>
<i>Most Respectfully, </i><br />
<i><br /></i>
<i>Dr Josh</i><br />
<i><br /></i>
<i>#tourettes</i><br />
<i>#tics</i><br />
<i><br /></i>
<i><br /></i>
<br />
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjUEwqBUlTaN5ODT7Rbq6z8-JPDNOTOKHiIWYp93aY5XhIbXWuJImoskl3tmzSnY2L_OBLuEmEzuNsxY0A4EzeWUwYvA6S4VveHbnrFWkakssRMEqh4StEITusA-aDysoyfQWCi/s1600/98B06CD2-CE12-4C07-B12E-9E3BA73FD3DF.jpeg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" data-original-height="895" data-original-width="1600" height="179" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjUEwqBUlTaN5ODT7Rbq6z8-JPDNOTOKHiIWYp93aY5XhIbXWuJImoskl3tmzSnY2L_OBLuEmEzuNsxY0A4EzeWUwYvA6S4VveHbnrFWkakssRMEqh4StEITusA-aDysoyfQWCi/s320/98B06CD2-CE12-4C07-B12E-9E3BA73FD3DF.jpeg" width="320" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Yes. Mr Gervais, neurologic problems are not funny. </td></tr>
</tbody></table>
<br />
<table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody>
<tr><td style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg6dxkTA6NshBKKRrGHYfQlkzqwcblX7GY8CHLT18aIn1yUTUUsp-NfPeU4W1eOfqvfnCersMnbAHY7ERMUvW7IjdamL44OrR8JbT8NBpN1DIBc3ah7Md3vfFzp-liQ4dZ0Daof/s1600/7F364B01-FC1D-41C5-86C1-BB1E108D6FA3.jpeg" imageanchor="1" style="margin-left: auto; margin-right: auto;"><img border="0" data-original-height="920" data-original-width="1600" height="183" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg6dxkTA6NshBKKRrGHYfQlkzqwcblX7GY8CHLT18aIn1yUTUUsp-NfPeU4W1eOfqvfnCersMnbAHY7ERMUvW7IjdamL44OrR8JbT8NBpN1DIBc3ah7Md3vfFzp-liQ4dZ0Daof/s320/7F364B01-FC1D-41C5-86C1-BB1E108D6FA3.jpeg" width="320" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;">Sneezing Tics are uncommon</td></tr>
</tbody></table>
<br />
<a href="https://youtu.be/gXJwHwZ3oi0">https://youtu.be/gXJwHwZ3oi0</a>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0tag:blogger.com,1999:blog-28898042.post-18162191579914362032020-01-26T08:38:00.003-06:002020-01-26T08:38:33.172-06:00Asperger was a Nazi who killed children. <i><b>How about we stop honoring this Nazi collaborator and murderer? </b><b>The Holocaust could not have happened without the collaboration of physicians who believed in <span style="-webkit-text-size-adjust: 100%; background-color: white; caret-color: rgb(51, 51, 51); color: #333333; font-family: nyt-imperial, georgia, "times new roman", times, serif;">lebensunwertes Leben or “</span><span style="-webkit-text-size-adjust: 100%; background-color: white; caret-color: rgb(51, 51, 51); color: #333333; font-family: nyt-imperial, georgia, "times new roman", times, serif;"> life unworthy of life,”</span></b></i><br />
<b><br /></b>
<b>Asperger <table cellpadding="0" cellspacing="0" class="tr-caption-container" style="float: right; margin-left: 1em; text-align: right;"><tbody>
<tr><td style="text-align: center;"><a href="https://ca-times.brightspotcdn.com/dims4/default/41cb4e5/2147483647/strip/true/crop/2048x1151+0+0/resize/840x472!/quality/90/?url=https%3A%2F%2Fcalifornia-times-brightspot.s3.amazonaws.com%2F1a%2Ffa%2Faebfd2b5b7e38f6edd2a9e8094bd%2Fla-1529021980-f20qkx9bia-snap-image" imageanchor="1" style="clear: right; margin-bottom: 1em; margin-left: auto; margin-right: auto;"><img border="0" data-original-height="450" data-original-width="800" height="179" src="https://ca-times.brightspotcdn.com/dims4/default/41cb4e5/2147483647/strip/true/crop/2048x1151+0+0/resize/840x472!/quality/90/?url=https%3A%2F%2Fcalifornia-times-brightspot.s3.amazonaws.com%2F1a%2Ffa%2Faebfd2b5b7e38f6edd2a9e8094bd%2Fla-1529021980-f20qkx9bia-snap-image" width="320" /></a></td></tr>
<tr><td class="tr-caption" style="text-align: center;"><span style="font-size: small;"><span style="-webkit-text-size-adjust: 100%; background-color: white; font-family: Georgia; text-align: start;">University of Vienna’s Children’s Hospital</span><br />where Asperger worked </span></td></tr>
</tbody></table>
”...protected children he deemed intelligent. But he also referred several children to Vienna’s Am Spiegelgrund clinic, which he undoubtedly knew was a centre of ‘child euthanasia’, part of what was later called Aktion T4. “</b><br />
<br />
<a href="https://www.nature.com/articles/d41586-018-05112-1">https://www.nature.com/articles/d41586-018-05112-1</a>Dr joshhttp://www.blogger.com/profile/05212400752434603954noreply@blogger.com0