Tuesday, March 22, 2011

ABSTRACT: Clinical features of childhood narcolepsy. Can cataplexy be foretold?
Nevsimalova S, Jara C, Prihodova I, Kemlink D, Sonka K, Skibova J.
Eur J Paediatr Neurol. 2011 Feb 21. [Epub ahead of print]

BACKGROUND: Narcolepsy is a life-long disease characterized by abnormal regulation of the sleep-wake cycle and increased penetration of rapid eye movement (REM) sleep. In children, narcolepsy without cataplexy is more frequently seen than in adults. The aim of our study was to evaluate clinical and polysomnographic parameters to verify if cataplexy appearing later in life can be foretold.

CONCLUSION: Narcolepsy in childhood leaves very little scope for the prediction of cataplexy later in life.

Read the full abstract here.

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