Monday, October 10, 2011

If You Don't Snooze, Do You Lose? Wake-Sleep Patterns Affect Brain Synapses During Adolescence

An ongoing lack of sleep during adolescence could lead to more than dragging, foggy teens, a University of Wisconsin-Madison study suggests. Researchers have found that short-term sleep restriction in adolescent mice prevented the balanced growth and depletion of brain synapses, connections between nerve cells where communication occurs.

"One possible implication of our study is that if you lose too much sleep during adolescence, especially chronically, there may be lasting consequences in terms of the wiring of the brain," says Dr. Chiara Cirelli, associate professor in the department of psychiatry at the School of Medicine and Public Health.

"Adolescence is a sensitive period of development during which the brain changes dramatically," Cirelli says. "There is a massive remodeling of nerve circuits, with many new synapses formed and then eliminated."

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