Wednesday, May 31, 2017

CBD and Epilepsy Seizures - A New Study

Image result for cannabidiolThis is a study of a pharmaceutical grade pill going through FDA approval. This is NOT a study of nutritional CBD.

The study observed a 22% reduction in seizures. 5% were seizure free. This will be a welcome addition, to therapy.

I always remind parents to watch this literature AND to watch reports of side effects of the agent.

This agent is NOT available in Texas.  CBD is not available from a Texas source at this time. Tough situation for kids- JR

Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome

Orrin Devinsky, M.D., J. Helen Cross, Ph.D., F.R.C.P.C.H., Linda Laux, M.D., Eric Marsh, M.D., Ian Miller, M.D., Rima Nabbout, M.D., Ingrid E. Scheffer, M.B., B.S., Ph.D., Elizabeth A. Thiele, M.D., Ph.D., and Stephen Wright, M.D., for the Cannabidiol in Dravet Syndrome Study Group*

N Engl J Med 2017; 376:2011-2020May 25, 2017DOI: 10.1056/NEJMoa1611618


The Dravet syndrome is a complex childhood epilepsy disorder that is associated with drug-resistant seizures and a high mortality rate. We studied cannabidiol for the treatment of drug-resistant seizures in the Dravet syndrome.


Among patients with the Dravet syndrome, cannabidiol resulted in a greater reduction in convulsive-seizure frequency than placebo and was associated with higher rates of adverse events. 

Preview Article HERE

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