A study claims that taking a specific type of antibiotic during pregnancy could increase the risk of epilepsy in their children.
A new study in Pediatric and Perinatal Epidemiology suggests that taking cystitis antibiotics during pregnancy increases risk of epilepsy in children.
J. E. Miller of School of Public Health, University of California, Los Angeles, CA and colleagues conducted the study and found taking cystitis antibiotics during pregnancy was associated with 10 to 20 percent increased risk of epilepsy in children.
For the study, researchers followed all liveborn singletons (447,629 children) born in Denmark between Jan 1996 and Sept 2004 for as long as 9.9 years. A total of 2,848 children were diagnosed with epilepsy during the follow-up.
Cystitis antibiotics included pivmecillinam, sulphamethizole and nitrofurantoin.
Children born to mothers who had redeemed prescriptions during pregnancy for pivmecillinam, sulphamethizole, and nitrofurantoin were 20%, 20% and 10% more likely to develop epilepsy, compared to those born to mothers who did not use antibiotics during pregnancy.
After adjustment for other factors, among mothers with multiple redeemed prescriptions during pregnancy, those taking pivmecillinam or sulphamethizole or nitrofurantoin were each associated with 30 percent increased risk of epilepsy in their children.
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