Tuesday, February 14, 2012

Scientists create brain cells from human skin in possible breakthrough for autism, Alzheimer's research


Brain and skin from common stem cells. JR

Scientists who have generated brain tissue from human skin are claiming a major breakthrough.
The researchers wrote on the University of Cambridge website that their findings could speed up the hunt for new treatments for diseases of the cerebral cortex, such as epilepsy and autism, to neurodegenerative conditions such as Alzheimer’s disease.
"Today’s findings will enable scientists to study how the human cerebral cortex develops, how it ‘wires up’ and how that can go wrong (a common problem leading to learning disabilities)," they wrote.
Their findings were published in the journal Nature Neuroscience.
Created cerebral cortex cells – those that make up the brain’s grey matter -- will allow them to "recreate brain diseases, such as Alzheimer’s, in the lab," they wrote, providing "previously impossible insight."
It may also allow them to develop and test new drugs to stop the diseases progressing.
Britain's Sunday Telegraph reported that until now, it has only been possible to generate tissue from the cerebral cortex by using controversial embryonic stem cells, obtained by the destruction of an embryo.
...
''We can study brain development and what goes wrong when it is affected by disease in a way we haven't been able to before. We see it as a major breakthrough in what will now be possible.''

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